The Influence of Risk Factors on Perioperative Results of Multivessel Coronary Artery Bypass Grafting Through the Left Anterior Minitoracotomy

O. Babliak, V. Demianenko, D. Babliak, A. Marchenko, E. Melnyk, K. Revenko, L. V. Pidgaina, O. Stohov
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引用次数: 0

Abstract

Multivessel coronary artery bypass grafting (CABG) through the left anterior minitoracotomy using the technique of total coronary revascularization via left anterior thoracotomy (TCRAT) is routinely performed in our institution since July 2017. This technique is used in all patients regardless of the number of anastomoses, quality and location of coronary targets, body mass index, age, comorbidities and predicted postoperative risk. The aim. To present the results of 349 consecutive patients with isolated multivessel coronary artery disease who underwent minimally invasive CABG. To compare perioperative outcomes of minimally invasive CABG in patients with existent risk factors for CABG and to identify possible contraindications to the use of this CABG technique. Materials and methods. From July 2017 to January 2020, 357 consecutive patients were underwent multivessel CABG at our institution. Eight (2.3%) patients in whom CABG was performed through the median sternotomy were excluded from the study. The remaining 349 (97.7%) patients underwent complete myocardial revascularization through the left anterior minitracotomy using TCRAT technique (peripheral cannulation for cardiopulmonary bypass (CPB), cold blood cardioplegia). All the patients were divided into groups according to the presence of risk factors (obesity, old age, diabetes, risk of postoperative mortality greater than 2.0 calculated by EuroSCORE II scale) to analyze the impact of these factors on intraoperative and postoperative parameters. Results. Intra- and postoperative parameters in patients of all groups were within safe limits. There was no statistically significant difference between the patients older and younger than 70. Diabetic and obese patients had a longer total operation time (on average by 5%, p = 0.003 and 7%, p = 0.019, respectively), CPB time (on average by 8%, p = 0.002 and 11%, p = 0.0001, respectively) and intensive care unit stay (on average by 15%, p = 0.004 and 17%, p = 0.013, respectively) compared to the patients without these conditions. The patients with EuroSCORE II risk more than 2.0 were had longer main phase of the operation (on average by 12 minutes, i.e. 8%, p = 0.013), they required longer ventilation time (by 27%, p = 0.036), longer stay in the intensive care unit (by 23%, p = 0.0004), had a longer hospital stay (by 15%, p < 0.0001), they were more likely to have acute kidney damage that required hemodialysis, and mortality was observed only in this group of patients. However, even in this group of severe patients, the incidence of complications and mortality did not exceed the predicted rates. Conclusions. The technique of minimally invasive CABG through the left anterior thoracotomy allow the possibility to avoid median sternotomy in 97.7% of patients with multivessel coronary artery disease. The technique of minimally invasive multivessel CABG through the left anterior thoracotomy is universal and does not require patient selection, because it can be used effectively and safely regardless of obesity, diabetes or old age. This technique can be performed in patients with any EuroSCORE II rate without the mortality rate increase.
危险因素对经左前小切口多支冠状动脉搭桥术围手术期疗效的影响
自2017年7月起,我院常规行左前开胸全冠状动脉重建术(TCRAT)经左前小切口行冠状动脉旁路移植术(CABG)。该技术适用于所有患者,不论吻合口数量、冠状动脉靶的质量和位置、体重指数、年龄、合并症和预测的术后风险。的目标。介绍349例连续行微创冠状动脉搭桥治疗的孤立性多支冠状动脉疾病患者的结果。比较存在CABG危险因素的患者微创CABG的围手术期结果,并确定使用该技术可能的禁忌症。材料和方法。2017年7月至2020年1月,我院连续357例患者行多血管冠脉搭桥。8例(2.3%)通过胸骨正中切开术行冠脉搭桥的患者被排除在研究之外。其余349例(97.7%)患者采用TCRAT技术(外周插管体外循环(CPB),冷血心脏截瘫)通过左前小切口行心肌血运重建术。所有患者根据是否存在危险因素(肥胖、高龄、糖尿病、术后死亡风险大于2.0的EuroSCORE II量表计算)进行分组,分析这些因素对术中及术后参数的影响。结果。各组患者的术中及术后参数均在安全范围内。年龄大于70岁的患者与年龄小于70岁的患者无统计学差异。糖尿病和肥胖患者的总手术时间(平均增加5%,p = 0.003和7%,p = 0.019)、CPB时间(平均增加8%,p = 0.002和11%,p = 0.0001)和重症监护病房时间(平均增加15%,p = 0.004和17%,p = 0.013)均高于无上述情况的患者。第二EuroSCORE患者风险超过2.0操作的主要阶段较长(平均12分钟,即8%,p = 0.013),他们需要再通风时间(27%,p = 0.036),再呆在重症监护病房(23%,p = 0.0004),住院时间较长(15%,p < 0.0001),他们更可能有急性肾损伤,需要血液透析,观察和死亡率只有在这组病人。然而,即使在这组重症患者中,并发症的发生率和死亡率也没有超过预期。结论。经左前开胸行微创冠状动脉搭桥术可避免97.7%的多支冠状动脉疾病患者胸骨正中切口。通过左前开胸行微创多血管冠脉搭桥技术是普遍的,不需要患者选择,因为无论肥胖、糖尿病或老年,都可以有效、安全地使用。该技术可用于任何EuroSCORE II评分的患者,而不会增加死亡率。
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