Cervical Cancer screening in a tertiary care centre by Pap smear and its clinical correlation

G. Sharma, R. Adhikari, Shyam Sundar Parajuly, K. Adhikari
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引用次数: 3

Abstract

Introduction: Cervical cancer is one of the common cancers in women and is a major public health problem all over the world. It has significant contribution to high mortality and morbidity. Preinvasive lesions spontaneously regress to normal, remain stable for a long time or progress to higher degree of dysplasia followed by carcinoma cervix. Materials and Method This was a hospital based retrospective study where 456 patients’ records were reviewed. Pap smear was used as the screening tool for the detection of precancerous lesion among the women visiting Western Regional Hospital (WRH), Department of obstetrics and gynecology. Results: Among 456 patients screened, most of them were in the age group of 30-39 years (42.8%) and were of parity 3 (42.8%). Most of them had no risk factors for carcinoma cervix (54.4%). Early marriage accounted for the highest risk of developing precancerous lesion (32.7%). There were no carcinoma detected by Pap smear. The test was negative in 68.9%, Low-grade Squamous Intraepithelial Lesion (LSIL) was detected in 5.9% and 2.9% had High-grade Squamous Intraepithelial Lesion (HSIL). Pap smear was sent for screening purpose in asymptomatic women (37.1%) and among the symptomatic patients vaginal discharge was the most common indication of pap test (34.6%). Conclusion: A Pap smear is reliable, simple, non-invasive, cost effective, and easy screening tool for detection of precancerous lesions in a woman.  
在三级保健中心进行子宫颈抹片检查及其临床相关性
宫颈癌是妇女常见的癌症之一,是世界范围内的一个重大公共卫生问题。它是造成高死亡率和高发病率的重要原因。侵袭前病变自发恢复正常,长期保持稳定或发展到较高程度的不典型增生,进而发生宫颈癌。材料与方法本研究以医院为基础,回顾了456例患者的病历。在西部地区医院妇产科就诊的妇女中,采用子宫颈抹片检查作为癌前病变的筛查工具。结果:筛查的456例患者中,30 ~ 39岁年龄组占42.8%,3胎位占42.8%。绝大多数(54.4%)没有宫颈癌的危险因素。早婚导致癌前病变的风险最高(32.7%)。巴氏涂片未检出癌。68.9%为阴性,5.9%为低级别鳞状上皮内病变(LSIL), 2.9%为高级别鳞状上皮内病变(HSIL)。无症状妇女(37.1%)接受巴氏涂片检查,有症状的患者中阴道分泌物是最常见的巴氏涂片检查指征(34.6%)。结论:巴氏涂片是一种可靠、简单、无创、经济、简便的筛查工具,可用于女性癌前病变的检测。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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