Gender Comparisons on Quality-of-Life and Comorbid Alcohol Dependence and Major Depression

S. Hyman, Ladan Khazai, Mousa Botros, Yadira I. Torres, J. Cornelius, Feng Miao, J. Mezzich, I. Salloum
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引用次数: 1

Abstract

Introduction and Objectives: Compared to men, substance-addicted women have greater social vulnerabilities that may impact their symptom presentation and overall quality-of-life (QOL). The latter is gaining prominence as an outcome measure and key element of person-centered care. We aimed to compare in this study treatment-seeking men and women with co-morbid alcohol dependence and major depression on measures of depression severity, addiction severity, and quality-of-life and to examine associations between addiction/depression severity and quality-of-life separately in men and women. Methods: Men (n = 34) and women (n = 33) participating in a psychopharmacology trial for co-morbid alcohol dependence and major depression were administered the Addiction Severity Index (ASI), the 25-item Hamilton Rating Scale for Depression (HAM-D), and the Multicultural Quality of Life Index at baseline as part of a large assessment battery. Results: Women reported greater global QOL impairment than men despite being similar on measures of depression and addiction severity. Depression severity, but not addiction severity, was significantly associated with QOL impairment in both men and women. Discussion and Conclusions: Treatment-seeking women with co-morbid major depression and alcoholism report lower QOL (i.e., happiness and life satisfaction) than their male counterparts. Depressive symptoms, but not addiction-related problems, may contribute to global QOL impairment. Alternatively, QOL impairment may increase depressed mood. Overall, QOL assessments may identify areas of impairment and opportunities for health promotion not assessed through traditional measures used in addiction treatment programs, and these measures may be more sensitive to the specific needs of women. Consideration of all these factors is likely to enhance person-centered care.
生活质量、共病酒精依赖和重度抑郁症的性别比较
前言和目的:与男性相比,物质成瘾的女性具有更大的社会脆弱性,这可能影响她们的症状表现和整体生活质量(QOL)。后者作为结果衡量标准和以人为本的护理的关键要素而日益突出。我们的目的是在本研究中比较寻求治疗的男性和女性共病酒精依赖和重度抑郁症患者在抑郁严重程度、成瘾严重程度和生活质量方面的测量,并分别检查男性和女性成瘾/抑郁严重程度和生活质量之间的关系。方法:参与酒精依赖和重度抑郁症共病精神药理学试验的男性(n = 34)和女性(n = 33)在基线时使用成瘾严重程度指数(ASI)、25项汉密尔顿抑郁评定量表(HAM-D)和多元文化生活质量指数作为大型评估系统的一部分。结果:尽管在抑郁和成瘾严重程度上相似,但女性报告的总体生活质量损害比男性更大。在男性和女性中,抑郁的严重程度与生活质量的损害显著相关,而非成瘾的严重程度。讨论与结论:寻求治疗的女性合并重度抑郁症和酒精中毒报告的生活质量(即幸福感和生活满意度)低于男性同行。抑郁症状,而不是成瘾相关问题,可能导致整体生活质量受损。另外,生活质量受损可能会增加抑郁情绪。总体而言,生活质量评估可以确定成瘾治疗方案中使用的传统措施无法评估的损害领域和促进健康的机会,这些措施可能对妇女的具体需求更为敏感。考虑所有这些因素可能会加强以人为本的护理。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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