Prevalence of Hepatitis B and C, Tuberculosis, and Human Immune Deficiency Virus among injection drug users of Punjab, Pakistan-A cross sectional study

Rabia Nawaz, H. Shakoor, M. Shahid, A. Ahad, S. Sabri, Anum Ajmal, Uqba Mehmood, Haroon Riaz, Faisal Rehman, S. Akhtar, A. Rehman, R. Rasheed, Muhammad Usman Kabir, Alina Jabeen, M. Sharif
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Abstract

Objective: To determine prevalence and factors associated with various infectious diseases such as Hepatitis B, Hepatitis C, HIV, and Tuberculosis, among injection drug users (IDUs), from different rehabilitation centers in several cities of Punjab region in Pakistan. Methods: This study was conducted between September, 2019 – September, 2020. Total 78 rehabilitation centers were contacted, out of which 21 responded and 57 didn't, even after having focus group discussions with the centers’ administrators. Centers contacted were chosen randomly over various cities of Punjab; with Lahore, Multan, Faisalabad, Gujranwala being major focus. A predesigned questionnaire with several open and closed ended questions was filled via interviewing each rehabilitation center administrator/staff to collect data for the study. Results: We found a prevalence of 7.96% for HBV, 9.61% for HIV, 0.82% for TB, and the highest 32.69% for HCV amongst the surveyed cohort. Conclusion: It is concluded that prevalence of infectious diseases in injection drug users is significantly higher than overall reported incidence, thus needs proper disease surveillance and mitigation programs on national level.
巴基斯坦旁遮普省注射吸毒者中乙型和丙型肝炎、结核病和人类免疫缺陷病毒的患病率-一项横断面研究
目的:确定来自巴基斯坦旁遮普省几个城市不同康复中心的注射吸毒者(IDUs)中乙型肝炎、丙型肝炎、艾滋病毒和结核病等各种传染病的患病率及其相关因素。方法:本研究于2019年9月- 2020年9月进行。我们总共联系了78家康复中心,其中21家做出了回应,57家没有回应,即使是在与康复中心的管理人员进行了焦点小组讨论之后。在旁遮普邦的各个城市中随机选择联系的中心;拉合尔、木尔坦、费萨拉巴德、古吉兰瓦拉是主要焦点。通过对每个康复中心的管理人员/工作人员进行访谈,填写预先设计的问卷,其中包含几个开放式和封闭式问题,以收集研究数据。结果:我们发现在调查队列中,HBV患病率为7.96%,HIV患病率为9.61%,TB患病率为0.82%,HCV患病率最高为32.69%。结论:注射吸毒者传染病流行率明显高于报告的总体发病率,需要在国家层面制定适当的疾病监测和缓解方案。
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