Design of Low Power & Low Noise On-Chip BioAmplifier in Cooperation with Analog IC Synthesis at 130nm Skywater Technology

Enes Saglican, Berkay Dur, Engin Afacan
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Abstract

Biomedical applications require sensor interface circuits to process considerably low level signals in amplitude and predispose them for digital signal processing (DSP). One of the building blocks of a sensor interface is the bioamplifier, where the signals acquired from the body (EMG, ECG, ENG etc.) are first conditioned under certain constraints such as low noise, high gain, etc. Considering all these constraints and challenging trade-offs among them, design of the bioamplifier may become very complicated to be performed manually. In this paper, we present a low noise and low power bioamplifier, which has been designed with the aid of an analog circuit synthesis tool. To this end, all sub-blocks of the bioamplifier have been optimized via a multi-objective analog optimization tool, then these sub-blocks have been assembled to achieve the final design. All designs have been realized using 130nm Skywater technology parameters. Post-layout simulations have indicated that the design has an input referred noise of 12.8 μV rms, 0.017 mm2 chip area, and 7.25 μW power consumption. Also, Monte Carlo analysis has showed that the circuit can operate properly even under the process variations.
低功耗低噪声片上生物放大器的设计与模拟集成电路合成在130nm Skywater技术
生物医学应用要求传感器接口电路处理幅度相当低的信号,并预先处理数字信号处理(DSP)。传感器接口的构建模块之一是生物放大器,其中从身体获得的信号(肌电图,ECG, ENG等)首先受到一定的限制,如低噪声,高增益等。考虑到所有这些限制和具有挑战性的权衡,生物放大器的设计可能变得非常复杂,无法手动执行。本文介绍了一种利用模拟电路合成工具设计的低噪声低功耗生物放大器。为此,通过多目标模拟优化工具对生物放大器的所有子模块进行优化,然后对这些子模块进行组装以实现最终设计。所有设计均采用130nm Skywater技术参数实现。布局后仿真结果表明,该设计的输入参考噪声为12.8 μV rms,芯片面积为0.017 mm2,功耗为7.25 μW。此外,蒙特卡罗分析表明,即使在工艺变化的情况下,电路也能正常工作。
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