Significance of pathogen identification for urinary tract infection and Helicobacter pylori infection in type 1 and type 2 diabetes mellitus patients

M. Rusalenko, M. Wisham, T. V. Konovalova, L. Lischenko, I. Savasteeva, N. I. Shevchenko
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Abstract

Objective. The aim of this study was to understand the significance of pathogen identification for Urinary tract infection and Helicobacter pylori infection in Diabetes Mellitus Type 1 and Diabetes Mellitus Type 2 patients.Materials and methods. The study was conducted among 1749 patients with Type 1 and Type 2 Diabetes Mellitus. Using microbiological techniques, the frequency of urinary tract infection was identified and the aetiology and sensitivity of microorganisms to antibacterial drugs were assessed. Data collected on Helicobacter pylori infection were verified through PCR tests on biopsies collected from the gastric mucosa.Results. The study showed that urinary tract infection has a high incidence rate with 58.3% of cases from Type 1 diabetes mellitus, and in 47.2% of cases from Type 2 diabetes. Pathogens such as Escherichia coli, Staphylococcus saprophyticus, Enterococcus faecalis and Klebsiella pneumoniae were the main causative agents of urinary tract infections. Helicobacter pylori infection was common in DM and more in cases of Type 2 Diabetes Mellitus at 27.1%, compared to cases in Type 1 Diabetes Mellitus at 22.8%. Also 5.9 % cases of Type 2 Diabetes Mellitus had combined Helicobacter pylori and urinary tract infections.Conclusion. The study showed the significance in identification of urinary tract infections and Helicobacter pylori infections in patients with Type 1 and Type 2 Diabetes Mellitus, and especially significant for Type 2 Diabetes Mellitus patients.
1型和2型糖尿病患者尿路感染和幽门螺杆菌感染病原菌鉴定的意义
目标。本研究旨在了解1型糖尿病和2型糖尿病患者尿路感染和幽门螺杆菌感染病原菌鉴定的意义。材料和方法。该研究在1749例1型和2型糖尿病患者中进行。应用微生物学技术,确定尿路感染的频率,评估微生物对抗菌药物的病原学和敏感性。通过对胃粘膜活检组织进行PCR检测,证实了幽门螺杆菌感染的数据。研究表明,尿路感染发生率较高,1型糖尿病患者发生率为58.3%,2型糖尿病患者发生率为47.2%。大肠杆菌、腐生葡萄球菌、粪肠球菌和肺炎克雷伯菌是尿路感染的主要病原体。幽门螺杆菌感染在糖尿病患者中很常见,在2型糖尿病患者中感染率为27.1%,而在1型糖尿病患者中感染率为22.8%。5.9%的2型糖尿病患者合并幽门螺杆菌和尿路感染。本研究对1型和2型糖尿病患者尿路感染和幽门螺杆菌感染的鉴别具有重要意义,尤其对2型糖尿病患者具有重要意义。
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