Urinary tract infection and vesicoureteric reflux

Snehamayee Nayak, N. Sharma, A. Jindal
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引用次数: 1

Abstract

Urinary tract infection (UTI) is one of the common causes of hospital visit in infants and children. Vesicoureteral reflux (VUR) predisposes to UTI and renal scarring. VUR is usually diagnosed after an episode of UTI. VUR is the most common underlying etiology responsible for febrile UTIs or pyelonephritis in children. Along with the morbidity of pyelonephritis, long-term sequelae of recurrent renal infections include renal scarring, proteinuria, and hypertension. Treatment is directed toward the prevention of recurrent infection through the use of continuous antibiotic prophylaxis during a period of observation for spontaneous resolution or by surgical correction. In children, bowel and bladder dysfunction (BBD) plays a significant role in the occurrence of UTI and the rate of VUR resolution. Effective treatment of BBD leads to higher rates of spontaneous resolution and decreased risk of UTI.
尿路感染和膀胱输尿管反流
尿路感染(UTI)是婴幼儿就诊的常见原因之一。膀胱输尿管反流(VUR)易导致尿路感染和肾瘢痕形成。VUR通常在尿路感染发作后被诊断出来。VUR是儿童发热性尿路感染或肾盂肾炎最常见的潜在病因。随着肾盂肾炎的发病率,复发性肾脏感染的长期后遗症包括肾瘢痕、蛋白尿和高血压。治疗的目的是通过在观察期间持续使用抗生素预防感染,以防止复发或通过手术矫正。在儿童中,肠道和膀胱功能障碍(BBD)在尿路感染的发生和VUR的缓解率中起着重要作用。有效治疗BBD可提高自发性消退率,降低尿路感染风险。
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