Nanostructured photonic biosensor for heavy metal detection design and development of porous silicon optical biosensors

J. Politi, P. Dardano, M. Iodice, I. Rea, L. de Stefano
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Abstract

Porous silicon (PSi) is interesting optical transducer in biosensors development. PSi can interact with biological and chemical species which penetrate inside the pores after a proper functionalization with specific bioprobes, producing a selective optical readout. In this work, we reported a functionalization approach to develop optical biosensors for heavy metal detection. Oligopeptides, namely Phytochelatins, were selected as bioprobes due to their ability to chelate heavy metal ions. Spectroscopic reflectometry and Fourier transform infrared spectroscopy were used as characterization techniques. Data show successful and repeatable functionalization process. These results are very good starting step in development of heavy metal ions optical biosensors.
用于重金属检测的纳米结构光子生物传感器的设计与研制
多孔硅(PSi)是生物传感器发展中很有前途的光学传感器。PSi可以与穿透毛孔内部的生物和化学物质相互作用,经过特定生物探针的适当功能化,产生选择性光学读数。在这项工作中,我们报告了一种功能化方法来开发用于重金属检测的光学生物传感器。寡肽,即植物螯合素,由于其螯合重金属离子的能力而被选择作为生物探针。光谱反射法和傅里叶变换红外光谱法作为表征技术。数据显示成功和可重复的功能化过程。这些结果为重金属离子光学生物传感器的研制提供了良好的开端。
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