Log-Exponential Power Distribution for Accelerated Failure Time Model in Survival Analysis and Its Application

Abstract

We proposed the log-exponential power density function as baseline distribution for accelerated failure time model (AFT) used in analysis of survival data with covariates. This model generalizes the log-normal and some exponential family due to flexibility at the tail region. It has log-concavity property, accommodates the four basic shapes of hazard function which is an attractive property compared with other distributions that cannot accommodate same. The model's goodness of fit relative to some existing models was tested using data from chronic liver disease patients monitored at Obafemi Awolowo University Teaching Hospital, Ile-Ife