Ischemic cardiomyopathy: Pathological Findings In A Case Of Stem Cell Implantation

A. Betigeri, Soma Guhathakurta, K. Cherian
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Abstract

The term “regenerative medicine” is a multidisciplinary field involving molecular and cell biologist, embryologist, pathologist, clinicians, bioengineers, and not to exclude ethicists. Early clinical studies, so for have indicate that, a stem cell implantation is feasible and has beneficial effect on infarcted heart. When compared to death of donor hearts for transplantation, complications associated with immunosupression, long-term failure of transplanted organs with high morbidity and mortality rates associated with myocardial infarction, stem cells scores over organ transplant. Most of the trials to date assessed cardiac function at 4-6 months after treatment and long-term outcome have not yet been described. Here in we present histopathological findings in explanted heart in a 50-year-old male patient who had received stem cell therapy for chronic ischemic heart disease.
缺血性心肌病:一例干细胞植入的病理发现
“再生医学”是一个多学科领域,涉及分子和细胞生物学家、胚胎学家、病理学家、临床医生、生物工程师,也不排除伦理学家。早期的临床研究表明,干细胞移植是可行的,并且对梗死心脏有有益的作用。与移植供体心脏的死亡、与免疫抑制相关的并发症、与心肌梗死相关的高发病率和死亡率的移植器官长期衰竭相比,干细胞评分高于器官移植。迄今为止,大多数试验评估了治疗后4-6个月的心功能和长期结果尚未描述。在这里,我们提出组织病理学结果在移植心脏在一个50岁的男性患者谁接受干细胞治疗慢性缺血性心脏病。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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