{"title":"Ischemic cardiomyopathy: Pathological Findings In A Case Of Stem Cell Implantation","authors":"A. Betigeri, Soma Guhathakurta, K. Cherian","doi":"10.5580/28a6","DOIUrl":null,"url":null,"abstract":"The term “regenerative medicine” is a multidisciplinary field involving molecular and cell biologist, embryologist, pathologist, clinicians, bioengineers, and not to exclude ethicists. Early clinical studies, so for have indicate that, a stem cell implantation is feasible and has beneficial effect on infarcted heart. When compared to death of donor hearts for transplantation, complications associated with immunosupression, long-term failure of transplanted organs with high morbidity and mortality rates associated with myocardial infarction, stem cells scores over organ transplant. Most of the trials to date assessed cardiac function at 4-6 months after treatment and long-term outcome have not yet been described. Here in we present histopathological findings in explanted heart in a 50-year-old male patient who had received stem cell therapy for chronic ischemic heart disease.","PeriodicalId":330833,"journal":{"name":"The Internet Journal of Thoracic and Cardiovascular Surgery","volume":"205 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Internet Journal of Thoracic and Cardiovascular Surgery","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5580/28a6","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
The term “regenerative medicine” is a multidisciplinary field involving molecular and cell biologist, embryologist, pathologist, clinicians, bioengineers, and not to exclude ethicists. Early clinical studies, so for have indicate that, a stem cell implantation is feasible and has beneficial effect on infarcted heart. When compared to death of donor hearts for transplantation, complications associated with immunosupression, long-term failure of transplanted organs with high morbidity and mortality rates associated with myocardial infarction, stem cells scores over organ transplant. Most of the trials to date assessed cardiac function at 4-6 months after treatment and long-term outcome have not yet been described. Here in we present histopathological findings in explanted heart in a 50-year-old male patient who had received stem cell therapy for chronic ischemic heart disease.