How molecular packets improve cell-to-cell communication

Abstract

Cells can communicate in multiple ways. Alongside the classic pathways of cellular communication, Extracellular Vesicles (EVs), can carry macromolecules of different nature (DNA, RNA, proteins, etc.) and thus they can be compared to packets carrying information that concur to stimulate different molecular pathways within the target cell. In this paper a model is proposed that evaluates the higher efficiency of cell-to-cell communication via EVs with respect to the classical ligand-receptor pathway.