Class 1 anti-arrhythmic drug provocation test

Abstract

The Brugada syndrome is associated with potentially lethal arrhythmias and sudden cardiac death. The diagnosis is made from the surface ECG. In suspicious but not typical ECGs, intravenous administration of class 1 anti-arrhythmic drugs (i.e. sodium channel blocking agents such as ajmaline, flecainide, or procainamide) can be performed for diagnostic reasons.