The effects of implanting different stents on the blood hemodynamic in coronary arteries

K. Hassani, K. Bajelani, M. Navidbakhsh
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Abstract

Stent implantation alters coronary artery hemodynamic and wall shear stress during cardiac cycles. In this study, three dimensional models were used to analyze the effects of different stent designs and strut thicknesses on the hemodynamic of the artery. The flow was assumed to be pulsatile and stent models were expanded in the artery the same as angioplasty procedure that uses balloon. The data was applied to Fluent-ANSYS package as a UDF MATLAB code. A non-slip condition was applied to the artery walls. The pressure variation in different stents and the wall shear stress distribution were studied. Furthermore, the hemodynamic effects on the flow were investigated for two different thickness values of the same stent design. These results showed that stent implanting is one of the main parameters of pressure drop in the artery. Moreover, the surface of the stent is the location of maximum wall shear stress and the thicker stent strut did not vary this stress much. Our study implies that some design parameters such as thickness affect the hemodynamic factors of blood after stent implantation. Even, stent implanting cause re stenosis in the coronary artery. Using new real models is suggested to investigate the new aspects of stent design and related effects on the hemodynamic of coronary arteries.
不同支架植入方式对冠状动脉血流动力学的影响
在心脏周期内,支架植入改变了冠状动脉血流动力学和壁剪应力。本研究采用三维模型分析不同支架设计和支架厚度对动脉血流动力学的影响。假设血流是脉动的,支架模型在动脉中扩张,与使用球囊的血管成形术相同。将数据作为UDF MATLAB代码应用到Fluent-ANSYS软件包中。动脉壁采用防滑条件。研究了不同支架内压力的变化及支架壁剪应力的分布。此外,研究了相同支架设计的两种不同厚度值对血流动力学的影响。这些结果表明,支架植入是动脉压降的主要参数之一。此外,支架表面是最大壁剪应力的位置,较厚的支架支撑对该应力变化不大。我们的研究表明,一些设计参数,如厚度,会影响支架植入后血液的血流动力学因素。甚至,支架植入会引起冠状动脉再狭窄。建议使用新的真实模型来研究支架设计的新方面及其对冠状动脉血流动力学的相关影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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