An Abnormal EEG Simulation Based on The Chay Model of An Excitable Neuron

Abstract

The work here presents an abnormal EEC simulation by using the electrophysiological model of the neuron. The spike wave and the multi-spike wave of the EEG morphology are reconstructed. The simulation model is derived from the Chay model, which describes the abnormal process in an excitable neuron via bifurcation. The abnormal process, that spiking can be transformed into bursting rapidly, can be observed in some disorder of the nerve system, such as epileptic seizure. The spike wave is simulated by step changes in the bifurcation parameter, which is proportion to the concentration of the intracellular calcium ions (|Ca|1 ). And, when the concentration of (|Ca|1 is sufficiently large, the multi-spike wave can also be reconstructed. The simulation work will be helpful to understand how the EEG morphology is formed from the microcosmic viewpoint