Preliminary Study of Bone Tumors Hyperthermia at Microwaves Using Magnetic Implants

M. B. Lodi, N. Curreli, C. Macciò, E. Marongiu, L. Mariani, A. Fanti, M. Bozzi, G. Mazzarella
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引用次数: 2

Abstract

Microwave hyperthermia as therapeutic modality in oncology can be the next breakthrough technology if translated properly to the clinical practice. For deep-seated tumors such as bone cancers, antennas and radiating sources fails in achieving therapeutic temperatures without overheating healthy tissues. In this framework, magnetic implant to be used as thermo-seeds exposed to a several kHz magnetic field were studied. So far, the possibility of using magneto-dielectric biocompatible implant for performing microwave hyperthermia was not studied. In this work, we propose a simplified mono-dimensional electromagnetic model to study the propagation in a multilayer structure by means of the wave-amplitude transmission method. The model is aimed at finding suitable properties of the bolus, to be used as matching medium, while determining a set of working frequency for performing an effective treatment using magnetic implants. Then, we investigate the temperature evolution to determine, preliminarily, the feasibility of this innovative treatment modality.
磁性植入体微波骨肿瘤热疗的初步研究
微波热疗作为肿瘤学的治疗方式,如果正确地转化为临床实践,可以成为下一个突破性的技术。对于像骨癌这样的深层肿瘤,天线和辐射源无法在不使健康组织过热的情况下达到治疗温度。在此框架下,研究了将磁性植入物作为热种子暴露在几kHz磁场下。到目前为止,使用磁介质生物相容性植入物进行微波热疗的可能性还没有研究。本文提出了一种简化的一维电磁模型,利用波幅透射法来研究电磁波在多层结构中的传播。该模型的目的是找到合适的弹丸属性,作为匹配介质,同时确定一组工作频率,以便使用磁性植入物进行有效的治疗。然后,我们研究了温度演变,初步确定了这种创新处理方式的可行性。
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