Abstract A02: Investigating the association between social disorganization, health-related quality of life (HRQL), and prostate cancer diagnoses in African American Men

C. Rodgers, S. Zenk, Karriem S. Watson, R. Winn, Rupert Evans, Catherine H Balthazar, I. Chukwudozie
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引用次数: 0

Abstract

This proposed population-based study initiated by the Early Stage Investigator from a collaborative National Cancer Institute (NCI) P20 grant between Governors State University and the University of Illinois at Chicago attempts to identify the influence of social disorganization on health-related quality of life (HRQL) in African American men living in south suburban Cook County in Illinois with prostate cancer diagnosis using the International Classification of Functioning, Disability and Health (ICF) to measure and map disability by zip code using the Geographic Information System (GIS). Although the diagnosis is 65% higher for African American men in the U.S, the relationship between prostate cancer diagnosis, health-related quality of life (HRQL), and social disorganization has not been fully examined. Pertinent experimental procedures proposed to examine this relationship include using U.S census data to obtain geographical characteristics of socially disorganized communities within south suburban Cook County in Illinois, assessing cases of prostate cancer diagnosis for African American men living in the parameters of the research, examining HRQL for these cases using ICF classifications, spatially mapping these prostate cases to determine SD, and completing a regression analysis based on HRQL and SD scores. Currently, prostate cancer is the number one cancer among all men in Illinois with 42,773 identified cases between 2002 and 2006 for all races (IDPH, Illinois Cancer Registry, 2008). Additionally, African American men living in Cook County have the highest rate for all racial groups at 227.1 per 100,000 between 2002 and 2006 (IDPH, Illinois Cancer Registry, 2008). More importantly, African American men tend to have fewer prostate-specific antigen (PSA) tests, increasing the risk for latent diagnosis and lower survival rates. These proposed data hypothesized that social disorganization might increase risk for prostate cancer rates and lower HRQL based on socioeconomic and environmental influences identified in the ICF. The proposed research attempts to identify preventable risk factors that would assist in the development of preventative care for men at risk for prostate cancer, and increasing the HRQL of African American men with a current diagnosis of prostate cancer. Citation Format: Carolyn D. Rodgers, Shannon Zenk, Karriem S. Watson, Robert Winn, Rupert Evans, Sr., Catherine Balthazar, Ifeanyi Beverly Chukwudozie. Investigating the association between social disorganization, health-related quality of life (HRQL), and prostate cancer diagnoses in African American Men [abstract]. In: Proceedings of the Tenth AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2017 Sep 25-28; Atlanta, GA. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2018;27(7 Suppl):Abstract nr A02.
摘要A02:调查非裔美国男性社会紊乱、健康相关生活质量(HRQL)和前列腺癌诊断之间的关系
这项基于人群的研究是由美国国家癌症研究所(NCI)的早期研究者发起的,由州长州立大学和伊利诺伊大学芝加哥分校合作提供P20资助,试图确定社会混乱对生活在伊利诺伊州库克县南郊的非裔美国男性健康相关生活质量(HRQL)的影响,这些男性使用国际功能分类进行前列腺癌诊断。残疾和健康(ICF)使用地理信息系统(GIS)按邮政编码测量和绘制残疾地图。尽管在美国,非裔美国男性的诊断率要高出65%,但前列腺癌诊断率、健康相关生活质量(HRQL)和社会紊乱之间的关系尚未得到充分研究。研究这种关系的相关实验程序包括:使用美国人口普查数据获取伊利诺伊州库克县南郊社会无序社区的地理特征,评估研究参数内生活的非裔美国男性前列腺癌诊断病例,使用ICF分类检查这些病例的HRQL,对这些前列腺病例进行空间映射以确定SD,并根据HRQL和SD评分完成回归分析。目前,前列腺癌是伊利诺伊州所有男性的头号癌症,2002年至2006年间,所有种族共有42,773例确诊病例(IDPH,伊利诺伊州癌症登记处,2008年)。此外,在2002年至2006年间,居住在库克县的非裔美国男性在所有种族群体中的发病率最高,为每10万人中有227.1人(IDPH,伊利诺伊州癌症登记处,2008年)。更重要的是,非裔美国男性倾向于较少的前列腺特异性抗原(PSA)测试,增加了潜在诊断的风险和较低的生存率。这些提出的数据假设,基于ICF中确定的社会经济和环境影响,社会混乱可能会增加前列腺癌发病率的风险,并降低HRQL。拟议的研究试图确定可预防的风险因素,这些因素将有助于对有前列腺癌风险的男性进行预防性护理,并提高目前诊断为前列腺癌的非裔美国男性的HRQL。引用格式:Carolyn D. Rodgers, Shannon Zenk, kariem S. Watson, Robert Winn, Rupert Evans, Sr., Catherine Balthazar, Ifeanyi Beverly Chukwudozie。调查非裔美国男性社会紊乱、健康相关生活质量(HRQL)和前列腺癌诊断之间的关系[摘要]。见:第十届AACR会议论文集:种族/少数民族和医疗服务不足人群的癌症健康差异科学;2017年9月25-28日;亚特兰大,乔治亚州。费城(PA): AACR;癌症流行病学杂志,2018;27(7增刊):摘要nr A02。
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