A Constructive approach to Numerical Mapping scheme of Nucleotides for Preprocessing in Machine Learning

C. Saravanakumar, N. Usha Bhanu
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引用次数: 1

Abstract

One of the major issues in the Bioinformatics discipline is to construct a method by which the precise protein-coding region can be identified in the intended nucleotide series. The exact spotting of protein coding regions in a nucleotide is valuable in numerous entities. For an instance, it aids in describing unique proteins, develop drugs, and furthermore in uncovering the developmental foundation of a specific living being. Digital Signal Processing (DSP) rooted technique is quite popular for identifying protein coding regions. The main fundamental stage of the DSP oriented prediction of exon, is to direct the nucleotide base to the numeric values. Choosing a numerical mapping configuration influences the characteristics of the DNA sequence, helping them to pinpoint the precise area of the exon. Over the most recent twenty years, a number of methods to map the nucleotides have been effectively utilized as a preprocessing stage for exon prediction. The proposed method of mapping a sequence outerforms other schemes in predicting the region of exons.
一种用于机器学习预处理的核苷酸数值映射方案的建设性方法
生物信息学学科的主要问题之一是构建一种方法,通过该方法可以在预期的核苷酸序列中确定精确的蛋白质编码区域。核苷酸中蛋白质编码区域的精确定位在许多实体中都是有价值的。例如,它有助于描述独特的蛋白质,开发药物,并进一步揭示特定生物的发育基础。数字信号处理(DSP)根植技术是蛋白质编码区识别的常用方法。面向DSP的外显子预测的主要基本阶段是将核苷酸碱基定向到数值。选择一个数字映射配置会影响DNA序列的特征,帮助他们精确定位外显子的精确区域。近二十年来,许多核苷酸图谱的方法已被有效地用作外显子预测的预处理阶段。所提出的序列映射方法在预测外显子区域方面优于其他方案。
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