Diabetic Macular Edema Among Diabetic Patients at The University of Gondar Tertiary Eye Care and Training Center, North West Ethiopia

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Abstract

Background: Diabetic macular edema (DME) is the most common cause of visual impairment in patients with diabetes mellitus. The prevalence of DME globally is around 6.8 % and in Ethiopia range from 5.7% to 11%. Different factors are associated with DME including poor glycemic control, longer duration, hypertension, dyslipidemia. Objective: To determine the prevalence and associated factors of diabetic macular edema among diabetic patients attending University of Gondar (UOG) hospital, tertiary eye care and training center, NW Ethiopia Methods:A hospital based cross-sectional study was conducted from March 2021 to October 2021. Socio-demographic, clinical and laboratory data of patients was gathered. The collected data was entered into epi-data 4.6 version, exported to SPSS version 20 and analyzed. Results: A total of 165 diabetic patients were enrolled with mean age of 54.71 ±13.66 years, 50.9% male, 85.5% urban dwellers, 79.9% type 2 DM,49.7% on oral hypoglycemic agents and the mean duration of diabetes was 7.93 years. Cataract was the commonest ocular morbidity and 42% of patients had at least mild vision impairment. The overall prevalence of DME was 17% and 5.5% of patients had clinically significant macular edema (CSME). The presence of proteinuria was 8.04 times more likely to have DME. Conclusion: The prevalence of DME among our patients was high. The presence of proteinuria was significantly associated with DME. Screening of diabetic patients for sight threatening retinopathy early and appropriate treatment is recommended.
埃塞俄比亚西北部冈达尔大学三级眼科保健和培训中心糖尿病患者的糖尿病性黄斑水肿
背景:糖尿病性黄斑水肿(DME)是糖尿病患者视力损害最常见的原因。二甲醚在全球的流行率约为6.8%,在埃塞俄比亚的流行率为5.7%至11%。与DME相关的因素包括血糖控制不良、持续时间较长、高血压、血脂异常。目的:了解埃塞俄比亚NW Gondar大学(UOG)医院三级眼科保健和培训中心糖尿病患者的糖尿病性黄斑水肿患病率及相关因素。方法:于2021年3月至2021年10月进行基于医院的横断面研究。收集患者的社会人口学、临床和实验室数据。将收集到的数据输入epi-data 4.6版本,导出到SPSS 20版本进行分析。结果:共纳入165例糖尿病患者,平均年龄54.71±13.66岁,男性50.9%,城市居民85.5%,2型糖尿病79.9%,口服降糖药49.7%,糖尿病平均病程7.93年。白内障是最常见的眼部疾病,42%的患者至少有轻度视力障碍。DME的总体患病率为17%,5.5%的患者有临床显著的黄斑水肿(CSME)。蛋白尿患者患二甲醚的可能性是其他患者的8.04倍。结论:二甲醚在我院患者中的患病率较高。蛋白尿的存在与DME显著相关。建议对糖尿病患者进行视力威胁视网膜病变的早期筛查和适当的治疗。
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