The effect of appropriate antibiotic use on the length of hospital stay in deep neck abscess (DNA) patients

Hesti Dyah Palupi, Dian Paramita Wulandari, Feri Trihandoko
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Abstract

Deep neck abscess (DNA) is an emergency in the otorhinolaryngology head and neck surgery field due to the formation of abscesses in the potential space between the deep neck fasciae. It is typically caused by the expansion of infection from various sources, including the teeth, mouth, throat, paranasal sinuses, middle ear, and neck. The increase of DNA cases needs for improvement of patient management especially when the patients have comorbidities which lead to an extended length of treatment. The study aimed to evaluate the appropriateness of empirical antibiotics given according to culture results and any comorbid factors that affect the length of hospital stay (LOHS). It was case-control observational study involving 44 cases of DNA patients who treated at Dr. Sardjito General Hospital Yogyakarta in the period of January 2018 to December 2020. The patients were divided into two groups with 22 patients in each group. The first group was the DNA patients with > 7 d LOHS and the second one was those with ≤ 7 d.  No significantly relationship was observed between variables evaluated included the appropriate antibiotic use  (p=0.546). However, dental caries (DC) was significantly related with the LOHS (p=0.015). In conclusion, there is no relationship between the appropriate antibiotic use and the LOHS. However, the DC is risk factor that influence the LOHS in patients with DNA.
适当使用抗生素对深颈脓肿(DNA)患者住院时间的影响
深颈脓肿(DNA)是耳鼻喉科头颈外科领域的一个急症,由于深颈筋膜之间的潜在空间形成脓肿。它通常是由各种来源的感染扩大引起的,包括牙齿、口腔、喉咙、鼻窦、中耳和颈部。DNA病例的增加需要改善患者管理,特别是当患者有合并症导致治疗时间延长时。本研究旨在根据培养结果和任何影响住院时间(LOHS)的合并症因素评估经验性抗生素的适宜性。这是一项病例对照观察性研究,涉及2018年1月至2020年12月期间在日惹Sardjito总医院接受治疗的44例DNA患者。将患者分为两组,每组22例。第1组为LOHS > 7 d的DNA患者,第2组为LOHS≤7 d的DNA患者。包括合理使用抗生素在内的评估变量之间无显著相关性(p=0.546)。龋齿(DC)与LOHS有显著相关性(p=0.015)。综上所述,抗生素的合理使用与LOHS之间没有关系。然而,DC是影响DNA患者LOHS的危险因素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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