Response to Baker and Fugh-Berman’s Critique of My Paper, 'Why Has Longevity Increased More in Some States than in Others?'

F. Lichtenberg
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引用次数: 64

Abstract

Dean Baker and Adriane Fugh-Berman have published a critique of a study I performed in 2007, entitled “Why has longevity increased more in some states than in others?” One of the conclusions I drew from that study was that medical innovation accounts for a substantial portion of recent increases in U.S. life expectancy. Baker and Fugh-Berman claim that my study was subject to a number of major methodological flaws. Many of their claims pertain to the role of infant mortality; the definition of drug vintage; the issue of age adjustment; and the appropriateness of controlling for AIDS, obesity, and smoking in the analysis of longevity. In this article, I make the case that their claims about my study are largely incorrect. I show that infant mortality was not an important determinant of the growth in U.S. life expectancy during the period that I studied, and that my estimates are completely insensitive to the inclusion or exclusion of infant mortality. Controlling for the age distribution of the population also has essentially no effect on the longevity equation estimates. I argue that my definition of drug vintage, based on the initial FDA approval year of a drug’s active ingredient, is quite reasonable, and it is consistent with the FDA’s evaluation of the therapeutic potential of new drugs. I argue that controlling for AIDS, obesity, and smoking in longevity analysis is entirely appropriate and consistent with the epidemiological literature. Baker and Fugh-Berman express deep skepticism about my study’s conclusion that medical innovation has played a very important role in recent U.S. longevity growth, but they offer no explanation of why life expectancy increased by almost a year during 2000-2006, a period of increasing poverty and obesity and declining health insurance coverage.
对Baker和Fugh-Berman对我的论文《为什么某些州的寿命比其他州长》的批评的回应?
迪恩·贝克(Dean Baker)和阿德里安·富格-伯曼(Adriane fuh - berman)对我在2007年进行的一项研究发表了一篇评论,题为“为什么某些州的寿命比其他州增长得更快?”我从这项研究中得出的一个结论是,医疗创新在美国人预期寿命最近的增长中占了相当大的一部分。Baker和Fugh-Berman声称我的研究存在一些主要的方法论缺陷。他们的许多主张与婴儿死亡率的作用有关;药品年份的定义;年龄调整问题;以及在寿命分析中控制艾滋病、肥胖和吸烟的适当性。在这篇文章中,我认为他们对我的研究的说法在很大程度上是不正确的。我表明,在我所研究的时期,婴儿死亡率并不是美国人预期寿命增长的一个重要决定因素,而且我的估计对包括或排除婴儿死亡率完全不敏感。控制人口的年龄分布对寿命方程的估计基本上没有影响。我认为我对药物年份的定义是相当合理的,基于FDA对药物活性成分的最初批准年份,它与FDA对新药治疗潜力的评估是一致的。我认为,在寿命分析中控制艾滋病、肥胖和吸烟是完全合适的,并且与流行病学文献一致。贝克和富格-伯曼对我的研究结论表示了深深的怀疑,即医疗创新在最近美国人寿命的增长中发挥了非常重要的作用,但他们没有解释为什么在2000-2006年期间预期寿命增加了近一年,这是一个贫困和肥胖加剧、医疗保险覆盖面下降的时期。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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