ACP vs CPP-ACP: The better formula for caries control

Abstract

Aim: To evaluate and compare the efficacy of two 5% sodium fluoride varnishes containing amorphous calcium phosphate and casein phosphopeptide amorphous calcium phosphate respectively on the plaque pH, salivary fluoride ion release and patient acceptability. Methods: Seventy children were selected from a residential school for the study. Baseline plaque pH, salivary fluoride ion levels were determined. Varnish application was made, and the plaque pH and salivary fluoride ion release were determined at 24 hours, 3 months’ and 6 months’ post varnish application. Patient acceptability was determined immediately after varnish application. Results: No difference in the plaque pH and salivary fluoride ion levels were obtained among the two study groups at all tested time intervals. However, there was a difference in the salivary fluoride ion levels at baseline and at all the three post interventional time periods for both the groups, i.e., at 24 hours (for Group 1 p= 0.00 for Group 2 p=0.00), at 3 months (for Group 1 p=0.00 for Group 2 p=0.00) and at 6 months (for Group 1 p= 0.00 for Group 2 p=0.00). There was no statistically significant difference was observed in the patient acceptability between the two groups (p=0.709). Conclusion: Both the fluoride varnishes can be considered to be equally efficacious when compared based on