Diagnostic Performance of the Frequency-Domain Third- Order Simplified Spherical Harmonics (SP3) Model on Rheumatoid Arthritis in Finger Joints

Abstract

This work focuses on the evaluation of frequency-domain 3rd-order simplified spherical harmonics (FD-SP3) model based image reconstruction with respect to its clinical utility to diagnose rheumatoid arthritis (RA). The results presented here show that the FD-SP3 model achieves clinically relevant sensitivity (88%) and specificity (93%) that compare favorably to the ERT while maintaining significant computational advantage over the ERT.