Fusion of DET and Time-Frequency Analysis for Obstructive Sleep Apnea Screening

Zhixuan Cui, Chunyu Li
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Abstract

Obstructive Sleep Apnea (OSA) is a common disease, whose main feature is repeated episodes of apnea and hypopnea during sleep, and always leading to waking up from sleep. Traditional Heart Rate Variability (HRV) analysis methods for OSA screening are divided into time domain analysis and frequency domain analysis. The time domain analysis has been widely used, it uses the statistical discrete trend analysis method to analyze the variation of heart rate and RR. The law of frequency domain analysis is to use the time domain signal of HRV to do spectrum analysis. However, traditional HRV analysis methods are linear analysis methods, and there are shortcomings such as ignoring the short-term volatility of data and being unable to measure complexity. Therefore, this experiment proposes to perform time domain analysis, frequency domain analysis, and nonlinear DET analysis on the PPG signals of 15 OSA patients and 15 normal people, a total of 30 subjects. Significance, specificity, and accuracy are contrasted. Finally, when the embedding dimension m=6 and the scale factor s=4, the DET method gets better results than the traditional time-domain and frequency-domain analysis methods on significance, accuracy and specificity of OSA screening. This provides a fresh perspective for OSA screening.
DET与时频分析融合筛查阻塞性睡眠呼吸暂停
阻塞性睡眠呼吸暂停(OSA)是一种常见病,其主要特征是睡眠中反复发作的呼吸暂停和低通气,并总是导致从睡眠中醒来。传统的心率变异性(HRV)分析方法分为时域分析和频域分析两种。时域分析得到了广泛的应用,它采用统计离散趋势分析方法来分析心率和RR的变化。频域分析规律是利用HRV的时域信号进行频谱分析。然而,传统的HRV分析方法是线性分析方法,存在忽视数据的短期波动性、无法度量复杂性等缺点。因此,本实验拟对15名OSA患者和15名正常人共30名受试者的PPG信号进行时域分析、频域分析和非线性DET分析。对比了重要性、特异性和准确性。最后,当嵌入维数m=6,尺度因子s=4时,DET方法在OSA筛查的显著性、准确性和特异性上均优于传统的时域和频域分析方法。这为OSA筛查提供了新的视角。
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