Test of the Randomness of Residuals and Detection of Potential Outliers for the Modified Gompertz Model Used in the Fitting of the Growth of Shigella flexneri

G. Uba, Bilal Ibrahim Dan-Iya
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Abstract

The formulation of hypotheses and the recommendation of experiments as the subsequent stages of the research process are both brought about as a result of the utilization of complicated computer models that make it possible to represent intricate biological processes. Because these systems rely on random data, this is a necessity for all parametric statistical assessment procedures. When the diagnostic tests reveal that the residuals make up a pattern, there are a few different treatment choices available to choose from. Two of these alternatives include running a nonparametric analysis or switching to a new model. In this study, we use the Wald-Wolfowitz runs test as a statistical diagnosis tool to determine whether or not the randomization conditions have been met. The runs test found that there were 5 total runs, although the randomness assumption predicted 7.46 runs. The null hypothesis is not rejected since the p-value is greater than 0.05; this suggests that there is no convincing evidence of the residuals' non-randomness; rather, the residuals represent noise. In addition, the Grubb’s outlier test shows no indication of an outlier, further corroborate the scenario of the adequacy of the modified Gompertz model used in the fitting of the growth of Shigella flexneri.
修正Gompertz模型用于拟合福氏志贺氏菌生长的残差随机性检验和潜在异常值检测
作为研究过程的后续阶段,假设的提出和实验的推荐都是由于使用了复杂的计算机模型,使其有可能表示复杂的生物过程。因为这些系统依赖于随机数据,这是所有参数统计评估程序的必要条件。当诊断测试显示残差构成一种模式时,有几种不同的治疗选择可供选择。其中两种选择包括运行非参数分析或切换到新模型。在本研究中,我们使用Wald-Wolfowitz运行检验作为统计诊断工具来确定是否满足随机化条件。运行测试发现总共有5个运行,尽管随机假设预测了7.46个运行。原假设不被拒绝,因为p值大于0.05;这表明没有令人信服的证据表明残差的非随机性;相反,残差代表噪声。此外,Grubb的异常值检验没有显示异常值的迹象,进一步证实了用于拟合福氏志贺氏菌生长的修正Gompertz模型的充分性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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