Atrial Fibrillation Driver Localization From Body Surface Potentials Using Deep Learning

Miguel Angel Cámara-Vázquez, Adrián Oter-Astillero, I. Hernández-Romero, Miguel, Rodrigo, Eduardo Morgado-Reyes, S. Guillem, Ó. Barquero-Pérez
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引用次数: 3

Abstract

Atrial fibrillation (AF) is characterized by complex and irregular propagation patterns. Multipoint intracardiac mapping systems present a limited spatial resolution, which makes it difficult to identify AF drivers and ablation targets. These AF onset locations and drivers responsible for AF perpetuation are main targets for ablation procedures. Although noninvasive electrocardiographic imaging (ECGI) and inverse problem-based methods have been tested during AF conditions, they need an accurate mathematical modeling of atria and torso to get good results. In this work, we propose to model the location of AF drivers from body surface potentials (BPS) as a supervised classification problem. We used deep learning techniques to address the problem. We were able to correctly locate the 92% and 96% of drivers in the test and training sets, respectively (accuracy of 0.92 and 0.96), while the Cohen's Kappa was 0.89 for both sets. Therefore, proposed method can help to identify target regions for ablation using a noninvasive procedure as BSP mapping.
基于体表电位的深度学习心房颤动驱动定位
心房颤动(AF)的特点是复杂和不规则的传播模式。多点心内标测系统空间分辨率有限,难以识别房颤驱动因素和消融目标。这些AF的发病部位和导致AF持续存在的因素是消融手术的主要目标。虽然无创心电图成像(ECGI)和基于逆问题的方法已经在房颤条件下进行了测试,但它们需要对心房和躯干进行精确的数学建模才能获得良好的结果。在这项工作中,我们提出将体表电位(BPS)作为一个监督分类问题来建模AF驱动程序的位置。我们使用深度学习技术来解决这个问题。我们能够在测试集和训练集中分别正确定位92%和96%的驾驶员(准确率分别为0.92和0.96),而两个集的Cohen's Kappa为0.89。因此,提出的方法可以帮助识别靶区域消融使用无创程序作为BSP映射。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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