Investigation of Glucose Sensor by using Plasmonic MIM Waveguide Based M

Lokendra Singh, N. Agrawal, C. Saha
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Abstract

This paper presents the utilization of metalinsulator- metal (MIM) plasmonic waveguide based Mach- Zehnder interferometer (MZI) for the artificial enzymatic detection of glucose concentration in blood and urine. The output of MZI model is attained by utilizing the concept of constructive interference at the output port. The outer side of sensing arm of MZI is facilitated with 10 nm thick layer of gold nanoparticles (AuNPs) to improve the sensitivity. Further, the specificity of sensing arm towards glucose molecules is enhanced by coating a layer of glucose oxidase (GOx). The sensing analysis of sensor model is done by testing it in the presence of glucose RI ranging from 1.335 – 1.339 (in blood) and 1.335 – 1.341 (in urine). The results states that the proposed sensor structure is capable to sense the presence of glucose concentration with autocorrelation coefficient and sensitivity of 99.7 % and 989.6 nm/RIU respectively. The complete analysis of proposed sensor model is carried out in the wavelength range from 1490 – 1610 nm under perfect matched layers (PML) as boundary conditions by using finite difference time domain (FDTD) method.
基于等离子体MIM波导的葡萄糖传感器研究
本文介绍了利用金属绝缘体-金属(MIM)等离子体波导马赫-曾德干涉仪(MZI)人工酶法检测血液和尿液中的葡萄糖浓度。MZI模型的输出是利用输出端口的相消干涉的概念来实现的。MZI传感臂外侧采用10 nm厚的金纳米颗粒(AuNPs),提高了灵敏度。此外,通过包裹一层葡萄糖氧化酶(GOx),增强了传感臂对葡萄糖分子的特异性。传感器模型的传感分析是通过在葡萄糖RI范围为1.335 - 1.339(血液)和1.335 - 1.341(尿液)的情况下进行测试来完成的。结果表明,该传感器结构能够感知葡萄糖浓度的存在,自相关系数为99.7%,灵敏度为989.6 nm/RIU。在完全匹配层(PML)作为边界条件下,利用时域有限差分(FDTD)方法对1490 ~ 1610 nm波长范围内的传感器模型进行了完整的分析。
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