Application and availability of indigenous, commercially available medicines in periodontology

Stuti Rai, Utkarsh Singh, V. Bains, R. Srivastava
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Abstract

Across the globe, there has been increasing interest in the study of medicinal plants and its use in ailing various oral diseases including periodontal disease. Various antibiotics such as tetracycline, amoxicillin, penicillin, and metronidazole and antiseptics such as chlorhexidine are commonly used in periodontal diseases, but they have many side effects. While indigenous medicine has not only less side effects but can also be effective in regulating the systemic conditions that have been associated with periodontal diseases such as diabetes and cardiovascular diseases. These natural extracts contain phytochemical compounds which have anti-inflammatory property, prevent bleeding, and antimicrobial properties. Several plant extracts such as curcumin, green tea, and neem have shown promising results in the field of periodontics. However, in the current scenario, the biggest challenge is the significant gap in research and lack of information regarding its interaction with the oral tissue, mechanism of action, and side effects. This study gives an insight into the current use of available herbal medicines that have been readily used in dental treatment particularly periodontal disease. It also gives information regarding the availability of these drugs through various platforms. It can be concluded that indigenous remedies have potential benefits in controlling plaque and inflammation as adjuncts to daily oral hygiene in patients with periodontitis gingivitis.
本地和市售药物在牙周病中的应用和可得性
在全球范围内,人们对药用植物的研究及其在包括牙周病在内的各种口腔疾病中的应用越来越感兴趣。四环素、阿莫西林、青霉素、甲硝唑等各种抗生素和氯己定等杀菌剂常用于牙周病,但它们有许多副作用。土著医学不仅副作用少,而且还能有效地调节与糖尿病和心血管疾病等牙周病有关的全身状况。这些天然提取物含有植物化学化合物,具有抗炎特性,防止出血和抗菌特性。几种植物提取物,如姜黄素,绿茶和楝树在牙周病领域显示出有希望的结果。然而,在目前的情况下,最大的挑战是研究的重大差距和缺乏有关其与口腔组织的相互作用,作用机制和副作用的信息。这项研究提供了一个深入了解目前使用的现有草药,已经很容易用于牙科治疗,特别是牙周病。它还提供了关于通过各种平台获得这些药物的信息。由此可见,作为牙周炎患者日常口腔卫生的辅助手段,乡土疗法在控制菌斑和炎症方面具有潜在的益处。
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