FNAC Diagnosis of Gallbladder Adenocarcinoma presenting as multiple skin Nodules and Jaundice

Abstract

Cutaneous metastasis is a rare manifestation of visceral malignancies, a phenomenon seen in 1% to 3% of all metastasizing tumors. A 62 years old female presented with multiple skin nodules in the neck and jaundice for 2 months. FNAC from the skin nodules revealed hypercellular smear composed of malignant epithelial cells arranged in clusters and glandular patterns. A provisional diagnosis of metastatic adenocarcinoma was given. USG and CT-scan of abdomen revealed a tumor in gallbladder fossa. USG guided FNAC and later on histopathological examination from the biopsy of the gallbladder tumor clinched the diagnosis of moderately differentiated gallbladder adenocarcinoma. Biopsy from the skin nodules revealed adenocarcinoma metastasis in skin. The patient was given postoperative chemotherapy and radiotherapy. Follow up period (3 months) was eventful.