Blood Pressure-to-height Ratios Can Identify Hypertension in Bantu Young Adults from Kinshasa in Democratic Republic of Congo

Danny Mafuta-Munganga, Benjamin Lupenzi-Masikini, Pascal Bayauli-Mwasa, Jean Bosco Kasiam-Lasi-On'Kin, Joseph Bidingija-Mabika, Symphorien Ditu-Mpandamadi, Remy Kapongo, Magloire Atantama, Dominique Mupepe-Mayuku, Jean-Marie Kayembe-Ntumba, Blaise Makoso-Nimi, B. Longo-Mbenza
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Abstract

Background: The diagnosis of hypertension in children and adolescents is not always easy. The blood pressure-to-height ratios (BPHR) have been proposed as a screening tool for diagnosing hypertension. Objective: To evaluate the diagnostic value of BPHR for detecting hypertension in young adults. Methods: A cross-sectional study was conducted among 12621 healthy young adults aged of 18-25 years in Kinshasa, from July 2018 to February 2019. Systolic blood pressure-to-height ratio (SBPHR) was calculated as systolic blood pressure (SBP) in mmHg devised by height in centimeter. Diastolic blood pressure-to-height ratio (DBPHR) was calculated as diastolic blood pressure (DBP) in mmHg devised by height in centimeter. The receiver operating characteristics (ROC) curve analysis had allowed determining the cut-off points of SBPHR and DBPHR to detect hypertension. Results: The prevalence of hypertension, prehypertension, obesity and overweight were 10.5%, 9.2%, 3.0% and 22.4% respectively. The median values of SBPHR were 0.75 (0.69-0.79) mmHg/cm and 0.77 (0.67-0.80) mmHg/cm respectively in men and in women. The median values of DBPHR were 0.48 (0.44-0.53) mmHg/cm and 0.51 (0.49-0.56) mmHg/cm respectively in men and in women. Optimal cutoff points of SBPHR to identify hypertensionwere0.81mmHg/cm and 0.89 mmHg/cm respectively in men and in women. The threshold of DBPHR to detect hypertension was 0.54 mmHg/cm in both men and women. SBPHR and DBPHR had high sensitivity and specificity for identifying hypertension. Conclusion: SBPHR and DBPHR can be used to detect hypertension in Bantu young adults in Kinshasa.
血压身高比可以识别来自刚果民主共和国金沙萨班图青年的高血压
背景:儿童和青少年高血压的诊断并不总是容易的。血压身高比(BPHR)已被提出作为诊断高血压的筛查工具。目的:探讨BPHR对青壮年高血压的诊断价值。方法:2018年7月至2019年2月,在金沙萨对12621名18-25岁的健康年轻人进行了横断面研究。收缩压高比(SBPHR)计算为收缩压(SBP)单位mmHg,高度单位厘米。舒张压高比(DBPHR)计算为舒张压(DBP)单位为mmHg,高度单位为厘米。受试者工作特征(ROC)曲线分析可以确定SBPHR和DBPHR的分界点来检测高血压。结果:高血压、高血压前期、肥胖和超重的患病率分别为10.5%、9.2%、3.0%和22.4%。男性和女性的SBPHR中位数分别为0.75 (0.69-0.79)mmHg/cm和0.77 (0.67-0.80)mmHg/cm。男性和女性DBPHR的中位值分别为0.48 (0.44-0.53)mmHg/cm和0.51 (0.49-0.56)mmHg/cm。男性和女性SBPHR识别高血压的最佳临界值分别为0.81mmHg/cm和0.89 mmHg/cm。无论男女,DBPHR检测高血压的阈值均为0.54 mmHg/cm。SBPHR和DBPHR对高血压的诊断具有较高的敏感性和特异性。结论:SBPHR和DBPHR可用于金沙萨班图青年高血压的检测。
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