Manejo anestésico para electroporación irreversible en el paciente pediátrico

Abstract

Introduction: Irreversible electroporation (IRE) is a technique known since 1972 incorporated into the oncological field in 2005 as a tumor ablation technique based on short high-voltage electrical pulses used to introduce chemical elements by diffusion, alter the cellular genetic structure, fuse a cell with other (reversible) or cause death (irreversible). These electric shocks carry an associated risk of cardiac arrhythmias, severe muscle contractions and seizures. Maintain an adequate anesthetic plane, optimal analgesia, deep neuromuscular relaxation and an electrocardiogram synchronized to the electrical pulses are the main objectives of anesthetic management. Objective: Describe the anesthetic implications of IRE in the pediatric patient. Material and methods: Narrative review based on a search for articles related to IRE in the most important databases, where the main source of information is case reports and non-systematic reviews of the literature, both in the area of anesthesiology and pain as well as engineering, vascular and cardiovascular interventional radiology, and surgery. Results: A total of 17 bibliographic references were found and reviewed. Conclusion: The anesthesia for IRE in the pediatric patient should guarantee an adequate anesthetic plane ideally with endotracheal intubation, optimal analgesia, deep relaxation and control of cardiac arrhythmias with electrocardiogram synchronization. Citar como: Moreno-Ravelo IA, Sánchez-Acosta P, Sarmiento-Argüello LA. Manejo anestésico para electroporación irreversible en el paciente pediátrico. Rev Mex Anestesiol. 2021; 44 (4): 277-281. https://dx.doi.org/10.35366/100873 Manejo anestésico para electroporación irreversible en el paciente pediátrico Anesthetic management for irreversible electroporation in the pediatric patient Dra. Ivón Alejandra Moreno-Ravelo,* Dr. Plácido Sánchez-Acosta,* Dra. Lina Andrea Sarmiento-Argüello*