Forensic DNA Phenotyping: A Review in Korean Perspective

H. Seo, Sohee Cho, J. Lee, S. Lyoo, M. Kim, Soong-Deok Lee
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引用次数: 7

Abstract

Current society understands the importance and capability of forensic DNA phenotyping (FDP), as a promising technique for supplementary investigative tool when the unknown short term repeat (STR) profile from person of interest fails to match anyone from DNA database [1,2]. In cases like these, FDP technique utilizes particular human externally visible characteristics (EVC) to deduce not only the physical appearance but also to estimate biological ages and even certain behavioral characteristics, such as smoking and alcohol consumption behaviors [1-4]. As FDP shows potential for its forensic operability by assuring reliable prediction results, Europe and America have already developed or in the process of developing prediction models, managing FDP as one of the investigative methods. Though Korea, as other Asian countries, is actively conducting researches regarding human EVCs, there are technological and administrative limitations for implementing such technique in Korea; further assessments and careful considerations are needed regarding the various aspects for introducing EVC Korean J Leg Med 2017;41:23-31 https://doi.org/10.7580/kjlm.2017.41.2.23
法医DNA表型:韩国视角的回顾
当前社会理解法医DNA表型(FDP)的重要性和能力,当嫌疑犯的未知短期重复序列(STR)图谱无法与DNA数据库中的任何人匹配时,FDP作为一种有前途的补充调查工具技术[1,2]。在这样的情况下,FDP技术利用特定的人类外部可见特征(EVC),不仅可以推断身体外观,还可以估计生物年龄,甚至某些行为特征,如吸烟和饮酒行为[1-4]。由于FDP能够保证可靠的预测结果,显示出其法医可操作性的潜力,欧美已经开发或正在开发预测模型,将FDP作为调查方法之一进行管理。虽然韩国与其他亚洲国家一样,正在积极开展人类EVCs的研究,但在韩国实施这种技术存在技术和行政限制;引入EVC的各个方面需要进一步的评估和仔细考虑。韩国医学杂志2017;41:23-31 https://doi.org/10.7580/kjlm.2017.41.2.23
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