The Effect of Having COVID-19 on Anti-Vaccination: Observational Prospective Study

Deniz Bilici, C. Doğan, Burcu Arpınar Yiğitbaş, E. Yazar, F. Eren
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Abstract

Objective: In this study, the effect of having had coronavirus disease-2019 (COVID-19) disease on anti-vaccination was investigated. Material and Methods: The study was conducted between February 2022-August 2022 in the COVID chest diseases clinic in our hospital. The cases who were COVID-19 vaccine hesitancy and not vaccinated against COVID-19 hospitalized in our clinic were included in the study. The level of anti-vaccination of the cases was measured with the Vaccine Hesitancy Scale (VHS). In addition, demographic informations such as age, gender, educational status, marital status, number of people living in the household, average monthly income, smoking history, and additional chronic diseases were recorded. Routine radiological and laboratory examinations, follow-up times in the clinic, and treatment results were recorded for cases like all patients hospitalized in our COVID chest diseases clinic. Results: 46 cases were included in the study. The mean age of the cases was 54.63+or-14.81 years, 24 (52.1%) were female. VHS was applied to all cases at the time of hospitalization. Since 6 cases were referred to the intensive care unit due to respiratory failure, the second VHS could not be applied to these cases, and these 6 cases were excluded from the study. A 2nd VHS was performed in the remaining 40 patients just before discharge. Each question score, A-B-C section score and total scale score were compared for the pre-COVID-19 and post-COVID-19 cases. While the VHS total score before COVID-19 infection was 36.48+or-7.36, the post-COVID-19 total score was found to be 25.65+or-9.10, a statistically significant decrease was observed (p < 0.001). It was observed that the mean scores of A-B-C decreased statistically in all sections (p < 0.001). Conclusion: As a result of our study, we found that the degree of anti-vaccine resistance decreased after the patients who were against the COVID-19 vaccine had the disease. As a result of our study, we found that the degree of COVID-19 vaccine hesitancy of patients decreased after they had the disease. We believe that conducting similar studies and sharing their results through mass media, can change the perspective of vaccine hesitancy individuals in society on this situation, especially during pandemic periods.
感染COVID-19对抗疫苗接种的影响:观察性前瞻性研究
目的:探讨新冠肺炎(COVID-19)感染对抗疫苗接种的影响。材料与方法:研究于2022年2月- 2022年8月在我院新冠肺炎胸部疾病门诊进行。本研究纳入我院住院的COVID-19疫苗犹豫且未接种COVID-19疫苗的病例。采用疫苗犹豫量表(VHS)测定病例的抗接种水平。此外,还记录了人口统计信息,如年龄、性别、教育状况、婚姻状况、家庭成员人数、平均月收入、吸烟史和其他慢性疾病。记录我院所有住院患者的常规影像学检查、实验室检查、门诊随访次数及治疗结果。结果:共纳入46例病例。平均年龄54.63±14.81岁,女性24例(52.1%)。所有病例住院时均采用VHS检查。由于6例患者因呼吸衰竭转至重症监护室,故第二次VHS无法应用于这些病例,因此这6例患者被排除在本研究之外。在出院前对其余40例患者进行第二次VHS检查。比较新冠肺炎前、后各问题评分、A-B-C部分评分和总量表评分。感染前VHS总分为36.48+or 7.36,感染后VHS总分为25.65+or 9.10,差异有统计学意义(p < 0.001)。各组A-B-C平均评分均有统计学差异(p < 0.001)。结论:我们的研究发现,接种COVID-19疫苗的患者发病后,抗疫苗耐药程度有所下降。通过我们的研究,我们发现患者在患病后对COVID-19疫苗的犹豫程度有所下降。我们认为,进行类似的研究并通过大众媒体分享其结果,可以改变社会上对疫苗犹豫不决的个人对这种情况的看法,特别是在大流行期间。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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