A non-invasive pulse pressure method for the estimation of total arterial compliance

P. Segers, N. Stergiopulos, P. Verdonck
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引用次数: 2

Abstract

With the Pulse Pressure Method (PPM; Stergiopulos et al., 1994), total arterial compliance can be estimated accurately from simultaneously measured aortic flow (Q/sub a0/) and pulse pressure (PP/sub a0/). The PPM is modified in 2 ways, yielding a non-invasive PPM (NIPPM): (i) Q/sub a0/ is replaced by a triangular flow, reconstructed from cardiac output, and is characterised by its base T/sub ej/ (systolic ejection time) and peak flow 2SV/T/sub ej/ (SV=stroke volume) at T/sub ej//3; (ii) PP/sub a0/ is estimated from a tonometric radial pressure measurement and a generalised aorta-radial pressure transfer function (TFF/sub g/). Application of the NIPPM on data from a group of hypertensive patients and young normotensive volunteers shows that (i) PP/sub a0/ is higher in the hypertensives for a same PP/sub r/ad; (ii) TAC is reduced from 2.11+/-0.51 ml/mmHg in the young volunteers to 1.13+/-0.51 ml/mmHg in the hypertensives.
一种用于估计动脉总顺应性的无创脉压法
采用脉冲压力法(PPM);Stergiopulos et al., 1994),可以通过同时测量主动脉流量(Q/sub a0/)和脉压(PP/sub a0/)准确估计动脉总顺应性。PPM通过两种方式进行修改,产生非侵入性PPM (NIPPM):(i) Q/sub a0/被由心输出量重建的三角形流量所取代,其特征在于其基数T/sub ej/(收缩期射血时间)和峰值流量2SV/T/sub ej/ (SV=冲程体积)在T/sub ej//3;(ii) PP/sub a0/由测压径向压力测量和广义主动脉-径向压力传递函数(TFF/sub g/)估算。NIPPM对一组高血压患者和年轻血压正常志愿者的数据的应用表明:(i)相同PP/sub / r/ad时,高血压患者的PP/sub / a0/更高;(ii) TAC从年轻志愿者的2.11+/-0.51 ml/mmHg降至高血压患者的1.13+/-0.51 ml/mmHg。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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