Role of nutrition in wound closure: a case report

Dania Ramírez Gonzalez, García Martinez Jorge Alberto, Ramirez Lopez Valeria Karina, González González Armando Francisco
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Abstract

Malnutrition is a common risk factor in chronic wounds due to its long healing period and it should be considered in their prevention. Nutrition during the wound-healing process should be adequate for the increased demand. The objective from this study is to present a case report of the evolution of a chronic infected wound after multidisciplinary management, including surgical approach, antibiotic therapy, and nutrition for its resolution. A 43-year-old female who begins with sudden pain in the left inguinal region associated with swelling. She received analgesic treatment without improvement and decided to attend the hospital where is diagnosed with septic shock secondary to soft tissue infection. Surgical drainage was done and a vulvar abscess was found, dissecting from the mount pubis to the ischiopubic fossa with necrotic tissue and fetid purulent material. In the postoperative period, multiple surgical lavages and debridements were carried out, followed by a VAC system. Nutritional parameters were below the acceptable level, parenteral nutrition was started and enteral nutrition with arginine boluses. Admission to the nutritional support service with parenteral nutrition and subsequently switching to enteral nutrition with arginine support raised their levels according to the improvement of the wound previously reported. Nutrient deficiency has been found in patients with chronic wounds and although the role of nutrition has not been adequately established, clinical improvement can be attributed to the establishment of treatment with complementary nutrition. Due to the good clinical response of our patient, we suggest formulas supplemented with arginine as part of the complete treatment (medical and surgical). The use of arginine dietary supplements in surgical patients leads to a consistent and significant reduction in postoperative infections.
营养在伤口愈合中的作用:1例报告
由于慢性伤口愈合时间长,营养不良是其常见的危险因素,应在预防中加以考虑。伤口愈合过程中的营养应满足增加的需求。本研究的目的是报告一例慢性感染伤口在多学科治疗后的演变,包括手术方法、抗生素治疗和营养解决。43岁女性,以左侧腹股沟区突然疼痛伴肿胀开始。她接受了镇痛治疗,但没有好转,并决定到医院就诊,诊断为继发于软组织感染的感染性休克。手术引流,发现外阴脓肿,从耻骨山到坐骨耻骨窝解剖坏死组织和恶臭脓性物质。术后进行多次手术洗胃和清创术,随后进行真空通气系统。营养指标低于可接受水平,开始肠外营养并给予精氨酸小丸肠内营养。根据先前报道的伤口改善情况,进入肠外营养支持服务并随后切换到精氨酸支持的肠内营养可提高其水平。在慢性伤口患者中发现了营养缺乏,尽管营养的作用尚未充分确定,但临床改善可归因于建立了补充营养治疗。由于患者的临床反应良好,我们建议将补充精氨酸的配方作为完整治疗(内科和外科)的一部分。在手术患者中使用精氨酸膳食补充剂可导致术后感染的持续和显著减少。
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