[About the temperature dependence of the bactericidal effect of some chemical disinfectants (author's transl)].

T Schliesser, J M Wiest
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Abstract

In quantitative suspension tests the influence of different temperatures (4 degrees C, 12 degrees C, 22 degrees C, 37 degrees C, +/- 2 degrees) on the bactericidal effect of formalin, phenol, sodium hydroxide peracetic acid with respect to gram-positive and gram-negative test germs (10(8) KBE/ml original culture) was examined. The results showed for formalin, phenol and sodium hydroxide a distinct temperature factor within the range of the germ-dependent, bactericidal limit concentrations. Compared with the temperature of about 22 degrees C which is normally applied in disinfectants tests revealed that at 12 degrees C the action time had at least to be doubled and at 4 degrees C the action time had to be four times as long for the complete killing of the germs. By contrast, with peracetic acid in its minimum effective concentrations (0.015 to 0.06%) a total germ reduction was attained after identical action times (5 minutes) at temperatures ranging between 4 degrees and 37 degrees C. Recommendations for the use of disinfectants must make allowance for the temperature factor.

【关于某些化学消毒剂杀菌效果的温度依赖性(作者译)】。
在定量悬浮试验中,考察了不同温度(4℃、12℃、22℃、37℃、+/- 2℃)对福尔马林、苯酚、氢氧化钠过氧乙酸对革兰氏阳性和革兰氏阴性试验细菌(10(8)KBE/ml原始培养物)的杀菌效果的影响。结果表明,福尔马林、苯酚和氢氧化钠在细菌依赖的杀菌极限浓度范围内存在明显的温度因子。与通常用于消毒剂的温度约为22摄氏度相比,试验表明,在12摄氏度下,作用时间至少要增加一倍,在4摄氏度下,作用时间必须增加四倍才能完全杀死细菌。相比之下,过氧乙酸在其最低有效浓度(0.015至0.06%)下,在4度至37度的温度范围内,经过相同的作用时间(5分钟),可以达到总细菌减少。使用消毒剂的建议必须考虑到温度因素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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