The role of M protein in phagocytosis. II. Opsonization of Streptococcus pyogenes in vitro.

S Tylewska, W Hryniewicz
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Abstract

Opsonization of two different streptococcal group A type 12 strains was investigated. The strains differed only in M protein presence. It was observed that after the treatment of bacteria with fresh normal rabbit serum M positive strains bind to their surface IgG only whereas M negative strains solely some complement components. These results may suggest that streptococci lacking M protein are able to activate complement by alternate pathway.

M蛋白在吞噬作用中的作用。2化脓性链球菌的体外调理。
研究了两种不同的A组12型链球菌的调理作用。不同的菌株只有M蛋白的存在。结果表明,经新鲜正常兔血清处理后,M阳性菌株仅与表面IgG结合,而M阴性菌株仅与部分补体成分结合。这些结果可能提示缺乏M蛋白的链球菌能够通过替代途径激活补体。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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