Influence factors on registration of three-dimensional contrast-enhanced ultrasound fusion imaging in evaluating the ablative margin - A phantom study.

IF 2.1 4区医学 Q3 HEMATOLOGY

Clinical hemorheology and microcirculation Pub Date : 2023-01-01 DOI:10.3233/CH-221573

Ruiying Zheng, Jieyi Ye, Xiaoer Zhang, Xiaoyu Zhou, Tongyi Huang, Ming Xu, Longfei Cong, Xiaoyan Xie, Guangliang Huang

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引用次数: 0

Abstract

Background: Registration of three-dimensional contrast-enhanced ultrasound fusion imaging (3DCEUS-FI) is time-consuming to obtain high success rate.

Objective: To investigate the influence factors on registration success rate of 3DCEUS-FI.

Methods: Water tank phantoms were made to obtain mimicked pre- and post- radiofrequency ablation three-dimensional contrast-enhanced ultrasound (3DCEUS) and CT images. Orthogonal trials were designed according to factors including size, depth, enhancement level of mimicked tumor, diameter and number of mimicked adjacent vessels. Mimicked pre- and post-RFA 3DCEUS images of 72 trials were fused to assess ablative margin (AM) by two radiologists. With CT images as standard, 3DCEUS-FI accuracy was considered as the consistency of AM evaluation. The inter-observer agreement and the influence factors on registration success rates were analyzed.

Results: The intraclass correlation coefficient (ICC) for the consistency of AM evaluation between CT and 3DCEUS-FI in x-axis, y-axis or z-axis was 0.840∼0.948 (P < 0.001). The ICC for inter-observer agreement was 0.840∼0.948 (P < 0.001). The success rates of registration within mimicked vessels with diameter of 2 mm were significantly lower than those with diameter of 3 mm and 4 mm.

Conclusions: The mimicked AM measured by 3DCEUS-FI had high accuracy and inter-observer agreement. Diameter of the mimicked adjacent vessels was significantly related to success rate of registration.

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三维增强超声融合成像在评估烧蚀边缘时配准的影响因素——一项幻象研究。

背景:三维对比增强超声融合成像(3DCEUS-FI)配准时间长，成功率高。目的:探讨影响3DCEUS-FI登记成功率的因素。方法:制作水罐模型，模拟射频消融前后的三维超声造影(3DCEUS)和CT图像。根据模拟肿瘤的大小、深度、增强程度、模拟邻近血管的直径和数目等因素设计正交试验。两名放射科医生将72例试验的模拟rfa前后3DCEUS图像融合以评估消融边缘(AM)。以CT图像为标准，以3DCEUS-FI精度作为AM评价的一致性。分析了观察者间的一致性和对注册成功率的影响因素。结果:CT与3DCEUS-FI在x轴、y轴和z轴上对AM评价一致性的类内相关系数(ICC)为0.840 ~ 0.948 (P)。结论:3DCEUS-FI测量的模拟AM具有较高的准确性和观察者间的一致性。模拟邻近血管的直径与配准成功率显著相关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical hemorheology and microcirculation 医学-外周血管病

CiteScore

4.30

自引率

33.30%

发文量

170

期刊介绍： Clinical Hemorheology and Microcirculation, a peer-reviewed international scientific journal, serves as an aid to understanding the flow properties of blood and the relationship to normal and abnormal physiology. The rapidly expanding science of hemorheology concerns blood, its components and the blood vessels with which blood interacts. It includes perihemorheology, i.e., the rheology of fluid and structures in the perivascular and interstitial spaces as well as the lymphatic system. The clinical aspects include pathogenesis, symptomatology and diagnostic methods, and the fields of prophylaxis and therapy in all branches of medicine and surgery, pharmacology and drug research. The endeavour of the Editors-in-Chief and publishers of Clinical Hemorheology and Microcirculation is to bring together contributions from those working in various fields related to blood flow all over the world. The editors of Clinical Hemorheology and Microcirculation are from those countries in Europe, Asia, Australia and America where appreciable work in clinical hemorheology and microcirculation is being carried out. Each editor takes responsibility to decide on the acceptance of a manuscript. He is required to have the manuscript appraised by two referees and may be one of them himself. The executive editorial office, to which the manuscripts have been submitted, is responsible for rapid handling of the reviewing process. Clinical Hemorheology and Microcirculation accepts original papers, brief communications, mini-reports and letters to the Editors-in-Chief. Review articles, providing general views and new insights into related subjects, are regularly invited by the Editors-in-Chief. Proceedings of international and national conferences on clinical hemorheology (in original form or as abstracts) complete the range of editorial features.