Intralesional curettage and cementation of low-grade chondrosarcomas of the appendicular skeleton: Long-term results from a single center.

IF 1.1 4区 医学 Q3 ORTHOPEDICS
Barış Görgün, Mahmut Kürşat Özşahin, Okan Tok, Cumhur Deniz Davulcu, Bedri Karaismailoğlu, Murat Hız
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引用次数: 0

Abstract

Objective: The purpose of this study was to investigate the results and complications in patients who had low-grade chondrosarcomas in the appendicular skeleton and were treated by intralesional curettage and cementation within the scope of 25 years of experience in a single center.

Methods: Ninety-one patients (72 female and 19 male) were retrospectively analyzed. The median at the time of surgery was 43 (17-78) years, and the median follow-up was 102 (26-288) months. All patients were treated by intralesional curettage followed by cementation with high-viscosity bone cement (polymethylmethacrylate). Complications and local recurrence rates, as well as clinical outcome scores were recorded.

Results: Five patients (5.49%) developed local recurrence at an average of 6.6 (6-9) months postoperatively. Four were treated with local wide excision and reconstruction with tumor prosthesis. One patient received recurettage and cementation. Two recurred patients were dedifferentiated into grade II chondrosarcomas in the last intervention. No major postoperative complication was identified in the series. Patients achieved an average Musculoskeletal Tumor Society scoring system of 92.4% (standard deviation 5.2; range 80-100) in the sixth postoperative month. Musculoskeletal Tumor Society scores in the recurrent patients decreased from an average of 90% to 75.3% after the final intervention.

Conclusion: Intralesional curettage and cementation seem safe and reliable techniques with low recurrence and complication rates in treating low-grade chondrosarcomas of the appendicular skeleton. Clinical, radiological, and pathological evaluations are mandatory before surgical intervention, and a multidisciplinary approach is crucial. A strict follow-up regimen in the early postoperative period is needed and strongly recommended to detect local recurrence.

Level of evidence: Level IV, Therapeutic Study.

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阑尾骨骼低级别软骨肉瘤的病灶内刮除和骨水泥:单一中心的长期结果。
目的:本研究的目的是探讨在单一中心25年的经验范围内,阑尾骨骼低级别软骨肉瘤患者行病灶内刮除和骨水泥治疗的结果和并发症。方法:回顾性分析91例患者的临床资料,其中女性72例,男性19例。手术时的中位年龄为43(17-78)岁,中位随访时间为102(26-288)个月。所有患者均行病灶内刮除,然后用高粘度骨水泥(聚甲基丙烯酸甲酯)进行骨水泥固化。记录并发症、局部复发率及临床结果评分。结果:5例(5.49%)患者局部复发,平均术后6.6(6-9)个月。4例行局部广泛切除及肿瘤假体重建。1例患者接受再结肠和骨水泥。2例复发患者在最后一次干预中去分化为II级软骨肉瘤。在该系列中未发现主要的术后并发症。患者达到肌肉骨骼肿瘤学会评分系统的平均92.4%(标准差5.2;范围80-100),术后第6个月。复发患者的肌肉骨骼肿瘤学会评分在最终干预后从平均90%下降到75.3%。结论:病灶内刮除和骨水泥治疗低级别阑尾骨骼软骨肉瘤安全可靠,复发率低,并发症发生率低。临床、放射学和病理学评估是手术前必须进行的,多学科的方法是至关重要的。术后早期需要严格的随访,强烈建议发现局部复发。证据等级:IV级,治疗性研究。
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来源期刊
CiteScore
2.00
自引率
0.00%
发文量
66
审稿时长
>12 weeks
期刊介绍: Acta Orthopaedica et Traumatologica Turcica (AOTT) is an international, scientific, open access periodical published in accordance with independent, unbiased, and double-blinded peer-review principles. The journal is the official publication of the Turkish Association of Orthopaedics and Traumatology, and Turkish Society of Orthopaedics and Traumatology. It is published bimonthly in January, March, May, July, September, and November. The publication language of the journal is English. The aim of the journal is to publish original studies of the highest scientific and clinical value in orthopedics, traumatology, and related disciplines. The scope of the journal includes but not limited to diagnostic, treatment, and prevention methods related to orthopedics and traumatology. Acta Orthopaedica et Traumatologica Turcica publishes clinical and basic research articles, case reports, personal clinical and technical notes, systematic reviews and meta-analyses and letters to the Editor. Proceedings of scientific meetings are also considered for publication. The target audience of the journal includes healthcare professionals, physicians, and researchers who are interested or working in orthopedics and traumatology field, and related disciplines.
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