Lactobacillus delbrueckii urinary tract infection in a male patient: a case report.

IF 1.7 Q3 INFECTIOUS DISEASES
GERMS Pub Date : 2022-06-30 eCollection Date: 2022-06-01 DOI:10.18683/germs.2022.1333
Ioannis K Neonakis, Iordanis Skamagkas, Dimitra Stafylaki, Sofia Maraki
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引用次数: 0

Abstract

Introduction: Lactobacilli are Gram-positive rods, commensals of the normal human flora. Generally, these lactic acid-producing bacteria are considered contaminants, however over the last years their clinical relevance is reevaluated. Lactobacillus delbrueckii is very rarely isolated and only a few cases of L. delbrueckii urinary tract infections (UTIs) have been reported, mainly in females.

Case report: We report the case of a L. delbrueckii UTI in an 82-year-old male suffering from benign prostate hyperplasia with repeated episodes of acute urinary retention over the last month before presenting to our hospital. The catheter urine culture grew >105 CFUs/mL of pure L. delbrueckii on Columbia CNA blood agar and on Trypticase soy agar. Identification was achieved by matrix-assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF MS), using VITEK MS (bioMérieux, France). The patient was successfully treated with cefixime for ten days. A follow-up urine culture performed 7 days after antibiotic discontinuation was sterile.

Conclusions: To our knowledge the present is the second case of L. delbrueckii urinary tract infection in a male patient. Further cases are required to confirm the clinical significance of these unusual pathogens and their involvement in human urinary tract infections.

一名男性患者的德尔布鲁贝克乳杆菌尿路感染:病例报告。
引言乳酸菌是革兰氏阳性杆菌,是人体正常菌群的共生菌。一般来说,这些产生乳酸的细菌被认为是污染物,但近年来,它们的临床意义被重新评估。德尔布鲁贝克乳杆菌很少被分离出来,仅有少数德尔布鲁贝克乳杆菌尿路感染(UTI)病例被报道,主要是女性:我们报告了一例 L. delbrueckii 尿路感染病例,患者是一名 82 岁的男性,患有良性前列腺增生症,在来我院就诊前的一个月内反复出现急性尿潴留。导尿管尿培养在哥伦比亚 CNA 血琼脂和胰酶大豆琼脂上生长出大于 105 CFUs/mL 的纯种德尔布鲁凯氏菌。使用 VITEK MS(法国生物梅里埃公司)的基质辅助激光解吸电离飞行时间质谱法(MALDI-TOF MS)进行了鉴定。患者接受了为期十天的头孢克肟治疗。停用抗生素 7 天后进行的尿液培养显示无菌:据我们所知,这是第二例男性患者发生德尔布鲁贝克氏菌尿路感染的病例。还需要更多病例来证实这些不常见病原体的临床意义及其在人类尿路感染中的参与。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
GERMS
GERMS INFECTIOUS DISEASES-
CiteScore
2.80
自引率
5.00%
发文量
36
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