Conservative Management of Spontaneous Left Main Coronary Artery Dissection (SCAD) Triggered by Emotional Stress in the Late Postpartum Period: Case Report and Pathophysiology.

IF 2.7 Q2 PATHOLOGY
Jaksa Zanchi, Dino Miric, Lovel Giunio, Anteo Bradaric Slujo, Mislav Lozo, Duje Erceg, Duje Orsulic, Josip A Borovac
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引用次数: 2

Abstract

A spontaneous coronary artery dissection (SCAD) during the postpartum period is a serious medical emergency and the most important non-atherosclerotic cause of coronary artery disease (CAD) in this population. While conservative management is recommended in most SCAD scenarios, cases complicated by hemodynamic instability or cardiogenic shock are particularly challenging and might be amenable only with invasive percutaneous or cardiothoracic surgical management. Herein, we present a case of a 35-year-old otherwise healthy woman that suffered an intense emotional stress event and was subsequently admitted with crushing chest pain to the emergency department. The initial electrocardiogram showed dynamic changes suggesting anterolateral ST-elevation myocardial infarction. She gave birth to a healthy child 3 months before the current presentation. Diagnostic angiography found no occlusive CAD but instead an extensive intramural hematoma originating from the left main artery dissection and extending to the whole left coronary circulation was observed. Hemodynamic instability and hypotension soon followed, and the patient went into cardiogenic shock. The heart team opted for conservative and supportive intensive care management without surgical or percutaneous intervention. This decision ultimately led to the successful extubation of the patient and the achievement of hemodynamic stability. The patient was eventually safely discharged home without any permanent disability.

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产后后期情绪应激诱发自发性左主干冠状动脉剥离(SCAD)的保守治疗:病例报告及病理生理学
产后自发性冠状动脉剥离(SCAD)是一种严重的医疗紧急情况,也是该人群中冠状动脉疾病(CAD)最重要的非动脉粥样硬化性原因。虽然大多数SCAD病例推荐保守治疗,但合并血流动力学不稳定或心源性休克的病例尤其具有挑战性,可能只能通过有创性经皮或心胸外科手术治疗。在此,我们提出一个35岁的健康女性的情况下,遭受了强烈的情绪应激事件,并随后承认粉碎胸痛到急诊科。初始心电图动态变化提示st段抬高前外侧心肌梗死。她在本次报告前3个月生下了一个健康的孩子。诊断性血管造影未发现闭塞性CAD,但观察到广泛的壁内血肿,起源于左主干夹层,并延伸到整个左冠状动脉循环。血流动力学不稳定和低血压紧随其后,患者进入心源性休克。心脏小组选择保守和支持性重症监护管理,没有手术或经皮介入。这一决定最终导致患者成功拔管并实现血流动力学稳定。病人最终安全出院回家,没有任何永久性残疾。
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来源期刊
Pathophysiology
Pathophysiology Medicine-Pathology and Forensic Medicine
CiteScore
3.10
自引率
0.00%
发文量
48
期刊介绍: Pathophysiology is an international journal which publishes papers in English which address the etiology, development, and elimination of pathological processes. Contributions on the basic mechanisms underlying these processes, model systems and interdisciplinary approaches are strongly encouraged.
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