Focused ultrasound: Innovation in use for neurologic conditions.

Trauma and emergency medicine Pub Date : 2022-01-01
Mohammad Hosseini, Kevin Pierre, Patrick Felisma, David Mampre, Allison Stein, Anna Fusco, Ramya Reddy, Vyshak Chandra, Brandon Lucke-Wold
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Abstract

Focused ultrasound has emerged as a key tool for neurologic disorders. In this focused review, we discuss the utility in disrupting the blood brain barrier to maximize treatment. This can facilitate creating direct coagulative lesions and aid in the administration of chemotherapy. Furthermore, it can facilitate neuromodulation when used in pulse sequencing. The current literature regarding brain tumors, essential tremor, and obsessive-compulsive disorder is reviewed. Additionally, concepts and experimental outcomes for neurodegenerative disease such as Alzheimer's is presented. Focused ultrasound as a tool is still in its infancy but the potential for adjuvant and direct therapy is promising. More clinical uses will become apparent in coming decades.

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聚焦超声:用于治疗神经系统疾病的创新。
聚焦超声已成为治疗神经系统疾病的重要工具。在这篇重点综述中,我们将讨论聚焦超声在破坏血脑屏障以最大限度地提高治疗效果方面的作用。这可以促进形成直接凝固病灶,有助于化疗的实施。此外,在脉冲序列中使用时,它还能促进神经调节。本文回顾了有关脑肿瘤、本质性震颤和强迫症的现有文献。此外,还介绍了阿尔茨海默氏症等神经退行性疾病的概念和实验结果。聚焦超声作为一种工具仍处于起步阶段,但其辅助和直接治疗的潜力令人期待。在未来几十年中,更多的临床应用将变得显而易见。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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