Genes and Regulatory Mechanisms for Ginsenoside Biosynthesis.

IF 2.2 4区生物学 Q2 PLANT SCIENCES

Journal of Plant Biology Pub Date : 2023-01-01 DOI:10.1007/s12374-023-09384-7

Padmanaban Mohanan, Tae-Jin Yang, Young Hun Song

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引用次数: 5

Abstract

Panax ginseng is a medicinal plant belonging to the Araliaceae family. Ginseng is known as the king of oriental medicine, which has been practiced since ancient times in East Asian countries and globally in the modern era. Ginseng is used as an adaptogen, and research shows that it has several pharmacological benefits for various ailments such as cancer, inflammation, diabetes, and neurological symptoms. The pharmacological benefits of ginseng are attributed to the triterpenoid saponin ginsenosides found throughout the Panax ginseng species, which are abundant in its root and are found exclusively in P. ginseng and Panax quinquefolius. Recently, with the completion of the entire ginseng genome sequencing and the construction of the ginseng genome database, it has become possible to access information about many genes newly predicted to be involved in ginsenoside biosynthesis. This review briefly summarizes the current progress in ginseng genome analysis and genes involved in ginsenoside biosynthesis, proposing directions for functional studies of the predicted genes related to ginsenoside production and its regulation.

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人参皂苷生物合成的基因及调控机制。

人参是五加科的一种药用植物。人参被称为东方医学之王，自古以来在东亚国家和现代世界都有使用。人参被用作一种适应原，研究表明它对癌症、炎症、糖尿病和神经系统症状等各种疾病有多种药理作用。人参的药理作用归因于在人参物种中发现的三萜皂苷人参皂苷，这些皂苷在人参根中含量丰富，仅在人参和西洋参中发现。近年来，随着人参全基因组测序的完成和人参基因组数据库的构建，许多新预测的参与人参皂苷生物合成的基因信息已成为可能。本文综述了人参基因组分析及人参皂苷合成相关基因的研究进展，并对人参皂苷合成相关基因的功能研究方向进行了展望。

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来源期刊

Journal of Plant Biology 生物-植物科学

CiteScore

5.40

自引率

3.40%

发文量

审稿时长

1 months

期刊介绍： Journal of Plant Biology, an official publication of the Botanical Society of Korea, is an international journal devoted to basic researches in biochemistry, cellular biology, development, ecology, genetics, molecular biology, physiology, and systematics of plants. The Journal publishes the following categories of paper: Original articles -- For publication in Journal of Plant Biology the manuscript must provide a significant new contribution to our understanding of plants. All areas of plant biology are welcome. No limit on the length, but a concise presentation is encouraged. Reviews -- Invited by the EiC. Brief Communications -- Concise but independent report representing significant contribution to plant science. The Botanical Society of Korea was founded on November 30, 1957 to promote studies, disseminate and exchange information on the field of plant biology. The first issue of The Korean Journal of Botany, the official publication of the society, was published on April 1, 1958. It was published twice a year, but quarterly from 5th volume in 1962. In 1994, it was renamed to Journal of Plant Biology and published in English since 1996. The journal entered its 50th year of publication in 2007.