Clinical outcomes of COVID-19 in patients with chronic diseases.

IF 0.9 Q3 MEDICINE, GENERAL & INTERNAL
Yasar Sertbas, Ebru Elci Solak, Selma Dagci, Volkan Kizilay, Zeynep Yazici, Serkan Elarslan, Kamil Ozdil
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Abstract

Objective: This study was carried out to evaluate the clinical outcomes of patients having chronic diseases (CD) and COVID-19 infection.

Methods: The study was carried out retrospectively by including 1.516 patients with CDs who applied to two education and research hospitals between June 01, 2021, and August 01, 2021, and were diagnosed with COVID-19. As CDs; cardiovascular diseases, diabetes mellitus (DM), hyperlipidemia, asthma, chronic obstructive pulmonary diseases, rheumatological diseases, malignancy, cerebrovascular disease, and chronic kidney diseases (CKD) were screened and evaluated statistically.

Results: A total of 1.516 patients with a mean age of 58.05±18.51 years were included in the study. It has been observed that 68.9% of COVID-19 patients have at least one CD. Women were more tend to have CDs than men (73.8% vs. 64.8%). Patients with a history of CD were significantly older and had a longer hospital stay than those without. Patients with CDs were 5.49 times more likely to be hospitalized in the intensive care unit (ICU) and their death rate was 2.52 times higher than the other patients. After the regression analysis, while hypertension (HT) (Odds Ratio [OR]: 2.39), DM (OR: 3.64), and any type of cancer (OR: 2.75) were seen as independent risk factors in hospitalizations in the ICU, cardiovascular diseases (OR: 2.27), CKD (OR: 3.69) and psychiatric disorders (OR: 2.18) were seen as independent risk factors associated with mortality.

Conclusion: The follow-up of COVID-19 patients with CDs should be done more cautiously than others. It should be kept in mind that patients with HT, DM, and cancer may need intensive care at any time of hospitalization, while those with cerebrovascular disease, CKD, and psychiatric problems may have a higher mortality rate than other patients.

COVID-19在慢性病患者中的临床结局
目的:评价慢性疾病(CD)合并COVID-19感染患者的临床结局。方法:回顾性研究纳入2021年6月1日至2021年8月1日在两家教育和科研医院申请的诊断为COVID-19的cd患者1.516例。cd;对心血管疾病、糖尿病(DM)、高脂血症、哮喘、慢性阻塞性肺疾病、风湿病、恶性肿瘤、脑血管疾病、慢性肾脏疾病(CKD)进行筛查和统计评价。结果:共纳入患者1.516例,平均年龄58.05±18.51岁。据观察,68.9%的COVID-19患者至少有一种CD,女性比男性更容易患有CD(73.8%比64.8%)。有乳糜泻病史的患者明显比没有乳糜泻病史的患者年龄更大,住院时间更长。cd患者在重症监护病房(ICU)住院的可能性是其他患者的5.49倍,死亡率是其他患者的2.52倍。回归分析后,高血压(HT)(优势比[OR]: 2.39)、糖尿病(OR: 3.64)和任何类型的癌症(OR: 2.75)被视为ICU住院的独立危险因素,心血管疾病(OR: 2.27)、CKD (OR: 3.69)和精神疾病(OR: 2.18)被视为与死亡率相关的独立危险因素。结论:COVID-19合并cd患者随访应谨慎。应该记住的是,HT、DM和癌症患者在住院的任何时间都可能需要重症监护,而脑血管疾病、CKD和精神疾病患者的死亡率可能高于其他患者。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Northern Clinics of Istanbul
Northern Clinics of Istanbul MEDICINE, GENERAL & INTERNAL-
CiteScore
0.40
自引率
0.00%
发文量
48
审稿时长
10 weeks
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