Clinical, dermoscopic and histological assessment of melanocytic lesions: a comparative study of the accuracy of the diagnostic methods.

IF 0.3 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL
Hippokratia Pub Date : 2021-10-01
E Kalloniati, D Cavouras, K M Plachouri, E Geropoulou, G Sakellaropoulos, S Georgiou
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引用次数: 0

Abstract

Background:   Worldwide, the incidence of melanoma is increasing, while late diagnosis is related to poor prognosis. A significant risk marker for melanoma is the presence of atypical nevi; therefore, it is of outstanding importance to make accurate clinical classification of common benign nevi, atypical nevi, and melanomas. The non-invasive method of dermoscopy allowed for the visualization of structures invisible to the naked eye and undoubtedly advanced the assessment of melanocytic lesions to a new dimension. This study aimed to evaluate the sensitivity and specificity of naked-eye examination and dermoscopy in diagnosing melanocytic lesions compared to the histopathological results, constituting the gold standard of diagnosis.

Material and methods: One hundred eighteen melanocytic lesions were clinically evaluated via the naked eye and dermoscopic examination, using Pattern Analysis Methodology, and afterward, they were excised. The histopathological results were correlated with the findings.

Results: According to the final histopathological analysis, 63 common benign nevi, 41 dysplastic nevi, and 14 cutaneous melanomas were excised in total. Clinical examination via the naked eye showed 78.2 % sensitivity and 71.4 % specificity in identifying the clinical atypia, while dermoscopy demonstrated 89.1 % sensitivity and 93.7 % specificity.

Conclusions: The results of the present study indicate a higher sensitivity and specificity of dermoscopy in evaluating and diagnosing melanocytic lesions compared to the naked-eye examination. HIPPOKRATIA 2021, 25 (4):156-161.

Abstract Image

黑色素细胞病变的临床、皮肤镜和组织学评估:诊断方法准确性的比较研究。
背景:在世界范围内,黑色素瘤的发病率正在增加,而晚期诊断与预后不良有关。黑色素瘤的一个重要风险标志是非典型痣的存在;因此,对常见的良性痣、非典型痣和黑色素瘤进行准确的临床分类具有重要意义。皮肤镜检查的非侵入性方法使肉眼看不见的结构可视化,无疑将黑色素细胞病变的评估提升到了一个新的层面。本研究旨在评估肉眼检查和皮肤镜检查在诊断黑色素细胞病变方面的敏感性和特异性,并与组织病理学结果进行比较,构成诊断的金标准。材料和方法:采用模式分析方法,通过肉眼和皮肤镜检查对118个黑色素细胞病变进行临床评估,然后将其切除。组织病理学结果与结果相关。结果:根据最终的组织病理学分析,共切除了63个常见的良性痣、41个发育异常痣和14个皮肤黑色素瘤。肉眼临床检查在识别临床异型性方面显示出78.2%的敏感性和71.4%的特异性,而皮肤镜检查显示出89.1%的敏感性和93.7%的特异性。结论:本研究结果表明,与肉眼检查相比,皮肤镜检查在评估和诊断黑色素细胞病变方面具有更高的敏感性和特异性。希波克拉蒂亚2021,25(4):156-161。
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来源期刊
Hippokratia
Hippokratia MEDICINE, GENERAL & INTERNAL-
CiteScore
1.10
自引率
0.00%
发文量
0
审稿时长
6-12 weeks
期刊介绍: Hippokratia journal is a quarterly issued, open access, peer reviewed, general medical journal, published in Thessaloniki, Greece. It is a forum for all medical specialties. The journal is published continuously since 1997, its official language is English and all submitted manuscripts undergo peer review by two independent reviewers, assigned by the Editor (double blinded review process). Hippokratia journal is managed by its Editorial Board and has an International Advisory Committee and over 500 expert Reviewers covering all medical specialties and additionally Technical Reviewers, Statisticians, Image processing Experts and a journal Secretary. The Society “Friends of Hippokratia Journal” has the financial management of both the printed and electronic edition of the journal.
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