Novel AI-Based Algorithm for the Automated Computation of Coronal Parameters in Adolescent Idiopathic Scoliosis Patients: A Validation Study on 100 Preoperative Full Spine X-Rays.

IF 2.6 3区 医学 Q2 CLINICAL NEUROLOGY
Global Spine Journal Pub Date : 2024-07-01 Epub Date: 2023-01-28 DOI:10.1177/21925682231154543
Clara Berlin, Sonja Adomeit, Priyanka Grover, Marcel Dreischarf, Henry Halm, Oliver Dürr, Peter Obid
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引用次数: 0

Abstract

Study design: Retrospective, mono-centric cohort research study.

Objectives: The purpose of this study is to validate a novel artificial intelligence (AI)-based algorithm against human-generated ground truth for radiographic parameters of adolescent idiopathic scoliosis (AIS).

Methods: An AI-algorithm was developed that is capable of detecting anatomical structures of interest (clavicles, cervical, thoracic, lumbar spine and sacrum) and calculate essential radiographic parameters in AP spine X-rays fully automatically. The evaluated parameters included T1-tilt, clavicle angle (CA), coronal balance (CB), lumbar modifier, and Cobb angles in the proximal thoracic (C-PT), thoracic, and thoracolumbar regions. Measurements from 2 experienced physicians on 100 preoperative AP full spine X-rays of AIS patients were used as ground truth and to evaluate inter-rater and intra-rater reliability. The agreement between human raters and AI was compared by means of single measure Intra-class Correlation Coefficients (ICC; absolute agreement; >.75 rated as excellent), mean error and additional statistical metrics.

Results: The comparison between human raters resulted in excellent ICC values for intra- (range: .97-1) and inter-rater (.85-.99) reliability. The algorithm was able to determine all parameters in 100% of images with excellent ICC values (.78-.98). Consistently with the human raters, ICC values were typically smallest for C-PT (eg, rater 1A vs AI: .78, mean error: 4.7°) and largest for CB (.96, -.5 mm) as well as CA (.98, .2°).

Conclusions: The AI-algorithm shows excellent reliability and agreement with human raters for coronal parameters in preoperative full spine images. The reliability and speed offered by the AI-algorithm could contribute to the efficient analysis of large datasets (eg, registry studies) and measurements in clinical practice.

基于人工智能的新算法用于自动计算青少年特发性脊柱侧凸患者的冠状面参数:对 100 张术前全脊 X 光片的验证研究
研究设计:回顾性、单中心队列研究:本研究的目的是验证一种基于人工智能(AI)的新型算法与人类生成的青少年特发性脊柱侧弯症(AIS)影像学参数的地面实况:开发的人工智能算法能够检测感兴趣的解剖结构(锁骨、颈椎、胸椎、腰椎和骶骨),并全自动计算AP脊柱X光片的基本放射学参数。评估的参数包括 T1 倾斜、锁骨角 (CA)、冠状平衡 (CB)、腰椎修正器以及近胸椎 (C-PT)、胸椎和胸腰椎区域的 Cobb 角。两名经验丰富的医生对 100 张 AIS 患者术前 AP 全脊柱 X 光片的测量结果被用作基本事实,并用于评估评分者之间和评分者内部的可靠性。通过单一测量的类内相关系数(ICC;绝对一致;>.75 为优秀)、平均误差和其他统计指标对人类评分员和人工智能之间的一致性进行了比较:结果:人类评分者之间的比较结果显示,评分者内部(范围:.97-1)和评分者之间(.85-.99)的 ICC 可靠性非常高。算法能够确定 100%图像的所有参数,ICC 值(.78-.98)极佳。与人类评分员一致的是,C-PT 的 ICC 值通常最小(例如,评分员 1A 与人工智能的比较:.78,平均误差:4.7°),CB(.96,-.5 毫米)和 CA(.98,.2°)的 ICC 值最大:结论:人工智能算法在术前全脊图像的冠状参数方面显示出极佳的可靠性,并与人类评分员的评分结果一致。人工智能算法的可靠性和速度有助于高效分析大型数据集(如登记研究)和临床实践中的测量。
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来源期刊
Global Spine Journal
Global Spine Journal Medicine-Surgery
CiteScore
6.20
自引率
8.30%
发文量
278
审稿时长
8 weeks
期刊介绍: Global Spine Journal (GSJ) is the official scientific publication of AOSpine. A peer-reviewed, open access journal, devoted to the study and treatment of spinal disorders, including diagnosis, operative and non-operative treatment options, surgical techniques, and emerging research and clinical developments.GSJ is indexed in PubMedCentral, SCOPUS, and Emerging Sources Citation Index (ESCI).
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