Feasibility analysis of a prevention programme for patients with early chronic disease using A mathematical model.

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Fanwen Meng, Aidan Lyanzhiang Tan, Bee Hoon Heng, Melvin Khee Shing Leow, Palvannan Kannapiran
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引用次数: 0

Abstract

The increasing prevalence of the chronic disease is of considerable concern to health-care organisations. Prevention programmes to patients with early chronic disease have the potential to improve individual health and quality of life through disease avoidance or delay and to save the medical cost of the health care system. Due to the limited budget in healthcare this study seeks to analyse the feasibility of a programme prior to implementation. A mathematical model is developed to determine incidence reduction rate at which the underlying cost break-even can be achieved; consequently, the programme would be feasible. We show the existence and uniqueness of the underlying incidence reduction and establish the feasibility frontier concerning the trade-offs between intervention effective period and incidence reduction rate. We use a diabetes prevention programme to demonstrate the efficiency and advantage of the model. The proposed model would inform decision-makers scientific principles in determining an intervention for implementation.

用数学模型分析早期慢性病患者预防方案的可行性。
慢性疾病的日益流行是卫生保健组织非常关注的问题。针对早期慢性疾病患者的预防规划有可能通过避免或延迟疾病改善个人健康和生活质量,并节省卫生保健系统的医疗费用。由于医疗保健预算有限,本研究旨在分析方案实施前的可行性。开发了一个数学模型,以确定发生率降低率,从而实现基本成本收支平衡;因此,该方案是可行的。我们证明了潜在发病率降低的存在性和唯一性,并建立了干预有效时间与发病率降低率权衡的可行性边界。我们用一个糖尿病预防项目来证明该模型的效率和优势。拟议的模式将为决策者提供确定执行干预措施的科学原则。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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