All Aortic Valve Diseases Taken Together Are Not Associated With Obesity.

Q3 Medicine

Critical Pathways in Cardiology Pub Date : 2022-12-01 DOI:10.1097/HPC.0000000000000298

Fathima Haseefa, Mohammad Reza Movahed, Sabrina Dahak, Mehrtash Hashemzadeh, Mehrnoosh Hashemzadeh

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引用次数: 0

Abstract

Background: Obesity is a risk factor for cardiovascular disease. The goal of this study was to evaluate any association between aortic valve disease and obesity using a very large database. Methods: The Nationwide Inpatient Sample database was utilized for statistical analysis using ICD-9 codes for aortic valve disease and obesity in the United States from 2003 to 2007. A 25% random sample of nonobese patients was used for comparison of aortic valve disease prevalence during the same 5-year period. Results: A total of 1,971,812 patients with obesity were identified from 2003 to 2007. Comparing this population with a random sample of nonobese patients during the same years, there was no significant difference between obese and nonobese patients in regards to the prevalence of aortic valve disease (1.1–1.2% in 2003 and 2004, 1.2% in 2005–2007, P = NS). After adjusting for age, gender, and race, obesity was associated with lower prevalence of aortic valve disease in 2003–2007 (odds ratio 0.81–0.86, P < 0.01). Conclusions: Using a very large database, we found a decrease in the prevalence of aortic valve disease in the obese population. This suggests that obesity alone does not pathologically affect the aortic valve.

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所有主动脉瓣疾病加在一起与肥胖无关。

背景:肥胖是心血管疾病的危险因素。这项研究的目的是通过一个非常大的数据库来评估主动脉瓣疾病和肥胖之间的关系。方法:利用全国住院患者样本数据库，采用ICD-9编码对2003 - 2007年美国主动脉瓣疾病和肥胖进行统计分析。随机抽取25%的非肥胖患者作为5年间主动脉瓣疾病患病率的比较样本。结果:2003 - 2007年共发现1,971,812例肥胖患者。将该人群与同期随机抽样的非肥胖患者进行比较，肥胖患者与非肥胖患者在主动脉瓣疾病患病率方面无显著差异(2003年和2004年为1.1-1.2%，2005-2007年为1.2%，P = NS)。在调整了年龄、性别和种族后，2003-2007年肥胖与主动脉瓣疾病的低患病率相关(优势比0.81-0.86,P < 0.01)。结论:通过一个非常大的数据库，我们发现肥胖人群主动脉瓣疾病的患病率有所下降。这表明肥胖本身不会对主动脉瓣产生病理影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Critical Pathways in Cardiology Medicine-Medicine (all)

CiteScore

1.90

自引率

0.00%

发文量

期刊介绍： Critical Pathways in Cardiology provides a single source for the diagnostic and therapeutic protocols in use at hospitals worldwide for patients with cardiac disorders. The Journal presents critical pathways for specific diagnoses—complete with evidence-based rationales—and also publishes studies of these protocols" effectiveness.