Trends in incidence of extrapulmonary tuberculosis in children in the Czech Republic in the past 35 years.

IF 1.1 4区医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Central European journal of public health Pub Date : 2022-12-01 DOI:10.21101/cejph.a7499

Karolína Doležalová, Vojtěch Kika, Dana Göpfertová, Jiří Wallenfels

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引用次数: 0

Abstract

Objective: Extrapulmonary tuberculosis (EPTB) in children globally represents a proportion of all cases of tuberculosis, reaching 20% according to published reports. Children are at a higher risk for disseminated TB and extrapulmonary forms. The most prevalent clinical presentations of EPTB in children worldwide are peripheral lymphadenitis and osteoarticular TB. Peritoneal, urogenital, or meningeal tuberculosis is less frequent, and their diagnosis is often difficult. The aim of the study was the determination of EPTB incidence in children in a low-prevalence region over 35 years.

Methods: Descriptive retrospective study of the incidence of EPTB in children and adolescents (aged 0-18 years) in the Czech Republic in the years 1987-2021 as reported in the tuberculosis register.

Results: Total amount of EPTB cases was 95. The most prevalent form was extrathoracic lymph node TB. The median age was 10 years. Most patients (84%) were Czechs. None of them died. The ratio of pulmonary and extrapulmonary TB was 79.8% to 20.2%.

Conclusion: The low incidence of EPTB in Czech children is congruent with a low incidence of TB in the Czech Republic. Our study confirms that the most frequent form of EPTB is peripheral lymph node TB. Our study did not prove a significant change in the trend of EPTB after the cessation of the mandatory Bacillus Calmette-Guerin (BCG) vaccination programme.

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过去35年捷克共和国儿童肺外结核发病率趋势

目的:根据已发表的报告，全球儿童肺外结核(EPTB)占所有结核病病例的比例，达到20%。儿童患播散性结核和肺外结核的风险较高。全世界儿童EPTB最普遍的临床表现是外周淋巴结炎和骨关节结核。腹膜结核、泌尿生殖结核或脑膜结核的发病率较低，诊断也很困难。该研究的目的是确定35岁以上低流行地区儿童EPTB发病率。方法:描述性回顾性研究捷克共和国1987-2021年结核病登记报告的儿童和青少年(0-18岁)EPTB发病率。结果:EPTB病例总数为95例。最常见的形式是胸外淋巴结结核。平均年龄为10岁。大多数患者(84%)是捷克人。没有人死亡。肺结核和肺外结核的比例分别为79.8%和20.2%。结论:捷克儿童EPTB低发病率与捷克共和国TB低发病率是一致的。我们的研究证实，EPTB最常见的形式是外周淋巴结结核。我们的研究没有证明在停止强制性卡介苗接种计划后EPTB的趋势有显著变化。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Central European journal of public health PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-

CiteScore

1.90

自引率

0.00%

发文量

期刊介绍： The Journal publishes original articles on disease prevention and health protection, environmental impacts on health, the role of nutrition in health promotion, results of population health studies and critiques of specific health issues including intervention measures such as vaccination and its effectiveness. The review articles are targeted at providing up-to-date information in the sphere of public health. The Journal is geographically targeted at the European region but will accept specialised articles from foreign sources that contribute to public health issues also applicable to the European cultural milieu.