Same-Day ART Initiation and Associated Factors Among People Living with HIV on Lifelong Therapy at Nekemte Specialized Hospital, Western Ethiopia.

IF 1.5 Q4 INFECTIOUS DISEASES

HIV AIDS-Research and Palliative Care Pub Date : 2023-01-01 DOI:10.2147/HIV.S395238

Lami Bayisa, Diriba Bayisa, Ebisa Turi, Diriba Mulisa, Tadesse Tolossa, Adugna Olani Akuma, Merga Chala Bokora, Dawit Tesfaye Rundasa

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Abstract

Background: The test-and-treat approach recommends early ART initiation (same day). Early ART start has double the benefits as treatment and as prevention. However, there is limited information regarding same-day ART initiation in Ethiopia. Hence, this study aimed to assess the magnitude and factors of same-day ART initiation among people living with HIV (PLHIV) on ART at Nekemte specialized hospital, in Western Ethiopia.

Methods: A cross-sectional study was conducted among 483 PLHIV from January 10 to February 15, 2021. Data were collected using an investigator-administered questionnaire. Epi Data 3.1 and STATA 14.0 were used for data entry and analysis, respectively. Variables with P-value <0.25 from bivariable analysis were included in the multivariable analysis. AOR with 95% CI and P-value <0.05 were used to declare statistical significance.

Results: A total of 483 study subjects participated and gave a 100% response rate. Two thirds (65%) of them started ART on the same day with a 95% CI [60.2-68.8]. Urban dwellers (AOR = 3.93 (95% 1.96-7.87)), with no OIs (AOR = 4.02 (95% CI: 1.54-10.47)), not screened for TB (AOR = 6.02 (95% CI: 1.71-21.15)), tested via VCT (AOR = 2.32 (95% CI: 1.37-3.26)), who have not used CPT (AOR = 1.88 (95% CI: 1.10-3.23)), who have not used IPT (AOR = 2.36 (95% CI: 1.0-5.57)), who were tested in 2019/20 (AOR = 2.37 (95% CI: 1.08-5.518)), and with BMI ≥25 kg/m² (AOR = 2.18 (95% CI: 1.05-4.52)) were significantly associated with same-day ART initiation.

Conclusion: Two thirds of study subjects initiated ART on the same day as HIV diagnosis. Voluntary testing and immediate referral to HIV care, advocating test-and-treat, and intensive counseling should be strengthened and reinforced for newly diagnosed HIV-positive people. Given that, high attention should be paid to individuals from urban residence, not screened for TB, who have not used CPT and IPT prophylaxis.

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在埃塞俄比亚西部Nekemte专科医院接受终身治疗的艾滋病毒感染者中，当日开始抗逆转录病毒治疗及其相关因素

背景:检测和治疗方法建议尽早开始抗逆转录病毒治疗(同一天)。早期开始抗逆转录病毒治疗具有治疗和预防双重效益。然而，关于埃塞俄比亚当日开始抗逆转录病毒治疗的信息有限。因此，本研究旨在评估埃塞俄比亚西部Nekemte专科医院艾滋病毒感染者(PLHIV)当天开始抗逆转录病毒治疗的程度和因素。方法:于2021年1月10日至2月15日对483例PLHIV患者进行横断面研究。数据是通过调查问卷收集的。使用Epi Data 3.1和STATA 14.0分别进行数据录入和分析。具有p值结果的变量:共有483名研究对象参与，反应率为100%。其中三分之二(65%)的患者在同一天开始ART治疗，95% CI[60.2-68.8]。城市居民(AOR = 3.93(1.96 - -7.87) 95%),没有OIs (AOR = 4.02(95%置信区间:1.54—-10.47)),不进行结核病筛检(AOR = 6.02(95%置信区间:1.71—-21.15)),测试通过VCT (AOR = 2.32(95%置信区间:1.37—-3.26)),没有使用CPT (AOR = 1.88(95%置信区间:1.10—-3.23)),没有使用IPT (AOR = 2.36(95%置信区间:1.0—-5.57)),测试在2019/20 (AOR = 2.37(95%置信区间:1.08—-5.518)),并与BMI≥25 kg / m2 (AOR = 2.18(95%置信区间:1.05—-4.52)明显与当天艺术启蒙。结论:三分之二的研究对象在HIV诊断当天开始抗逆转录病毒治疗。应加强和加强对新诊断的艾滋病毒阳性患者的自愿检测和立即转介艾滋病毒护理、倡导检测和治疗以及密集咨询。鉴于此，应高度重视未进行结核病筛查、未使用CPT和IPT预防的城市居民。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

HIV AIDS-Research and Palliative Care INFECTIOUS DISEASES-

CiteScore

3.00

自引率

6.70%

发文量

审稿时长

16 weeks

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