Decomposition of disparities in life expectancy with applications to administrative health claims and registry data

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
I. Akushevich , A. Yashkin , M. Kovtun , E. Stallard , A.I. Yashin , J. Kravchenko
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Abstract

Research shows that geographic disparities in life expectancy between leading and lagging states are increasing over time while racial disparities between Black and White Americans have been going down. In the 65+ age strata morbidity is the most common cause of death, making differences in morbidity and associated adverse health-related outcomes between advantaged and disadvantaged groups an important aspect of disparities in life expectancy at age 65 (LE65). In this study, we used Pollard’s decomposition to evaluate the disease-related contributions to disparities in LE65 for two types of data with distinctly differing structures: population/registry and administrative claims. To do so, we analyzed Pollard’s integral, which is exact by construction, and developed exact analytic solutions for both types of data without the need for numerical integration. The solutions are broadly applicable and easily implemented. Applying these solutions, we found that the largest relative contributions to geographic disparities in LE65 were chronic lower respiratory diseases, circulatory diseases, and lung cancer; and, to racial disparities: arterial hypertension, diabetes mellitus, and cerebrovascular diseases. Overall, the increase in LE65 observed over 1998–2005 and 2010–2017 was primarily due to a reduction in the contributions of acute and chronic ischemic diseases; this was partially offset by increased contributions of diseases of the nervous system including dementia and Alzheimer’s disease.

利用行政健康索赔和登记数据分解预期寿命差异。
研究表明,领先州和落后州之间预期寿命的地理差异随着时间的推移而增加,而美国黑人和白人之间的种族差异一直在下降。在65岁以上的年龄层中,发病率是最常见的死亡原因,这使得优势群体和弱势群体之间的发病率差异和相关的不良健康相关结果成为65岁预期寿命差异的一个重要方面(LE65)。在这项研究中,我们使用Pollard分解来评估两种结构明显不同的数据(人口/登记和行政索赔)对LE65差异的疾病相关贡献。为此,我们分析了Pollard积分,它通过构造是精确的,并为这两种类型的数据开发了精确的解析解,而不需要数值积分。这些解决方案适用范围广,易于实施。应用这些解决方案,我们发现对LE65地理差异的最大相对贡献是慢性下呼吸道疾病、循环系统疾病和癌症;种族差异:动脉高血压、糖尿病和脑血管疾病。总体而言,1998-2005年和2010-2017年期间观察到的LE65的增加主要是由于急性和慢性缺血性疾病的影响减少;这部分被包括痴呆症和阿尔茨海默病在内的神经系统疾病的增加所抵消。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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